Reaction profile

The FDA adverse-event record for pr-skin, lesion(s)

675 FDA adverse-event reports reference pr-skin, lesion(s) (VeDDRA 99673). See the species, breeds, and drugs most associated with it below.

675
reports citing this reaction
13.6%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
675
Total Reports
92
Deaths
13.6%
Death Rate

Species Most Affected

Dog 549
Cat 111
Cattle 8
Horse 4
Fish 1
Human 1
Mouse 1

Breeds Most Affected

Retriever - Labrador 61
Domestic Shorthair 43
Crossbred Canine/dog 41
Domestic (unspecified) 39
Retriever - Golden 36
Boxer (German Boxer) 25
Terrier - Bull - American Pit 20
Shih Tzu 19
Shepherd Dog - German 17
Bulldog 13

Associated Drugs

Oclacitinib Maleate 278
Cefovecin 73
Carprofen 51
Cyclosporine 41
Cefovecin Sodium 37
Cefpodoxime Proxetil 36
Maropitant Citrate 36
Selamectin 33
Prednisone 25
Moxidectin 22
Prednisolone; Trimeprazine Tartrate 22
Meloxicam 20
Enrofloxacin 20
Anti-Il31 Mab Mcs Lot #1283563 19
Methylprednisolone Acetate 18
Anesthetic 18
Cephalexin 14
Buprenorphine 14
Fluralaner Chew Tablets 14
Imidacloprid + Moxidectin 13

PR-SKIN, LESION(S) Reaction Insights

675 reports name PR-SKIN, LESION(S); 92 recorded a death outcome (13.6% of reported events, not a population-level mortality rate). VeDDRA code: 99673.

By species: Dog (549 reports), Cat (111 reports), Cattle (8 reports). By breed: Retriever - Labrador (61), Domestic Shorthair (43), Crossbred Canine/dog (41).

Most co-reported drugs: Oclacitinib Maleate (278 reports), Cefovecin (73 reports), Carprofen (51 reports), Cyclosporine (41 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.