Reaction profile

The FDA adverse-event record for low pancreatic enzymes

127 FDA adverse-event reports reference low pancreatic enzymes (VeDDRA 2694). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1276 of 2,481
by report volume (all reactions)
127
reports citing this reaction
18.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Low pancreatic enzymes has 127 reports now versus 125 in that prior snapshot: 2 more (1.6%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Low pancreatic enzymes changes

FDA AER · VeDDRA plate

Code 2694 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 127 reports
  • DEATH-ELEV 18.1%
  • MID-PACK #1276/2481
  • PHOTO-FINISH Cyst NOS
  • SPECIES-DOG Dog · 105
  • DRUG-LEAD Fluralaner 13.64%… · 22
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cyst NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Low pancreatic enzymes

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cyst NOS · near127HYPERBILIRUBINEMIA · near127INEFFECTIVE, WEIGHT L… · near127Low pancreatic enzymes · thi…127Mammary gland neoplas… · near127Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Low pancreatic enzymes

What the FDA AER plate says about Low pancreatic enzymes

Signature read: death-coded share at 18.1% is the most distinctive outcome stamp on Low pancreatic enzymes. Report volume sits in the middle third of the reaction corpus. 23 of 127 reports were death-coded (18.1% of named reports, not a population mortality rate). Nearest volume peer: Cyst NOS (±0 reports). Lead species Dog (105). Lead co-reported drug Fluralaner 13.64% 12-Week Chew (22).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Fluralaner 13.64% 12-Week Chew appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 105
Cat 21
Horse 1

Breeds Most Affected

Crossbred Canine/dog 15
Domestic Shorthair 14
Siberian Husky 8
Chihuahua 7
Shih Tzu 7
Terrier - Yorkshire 7
Retriever - Labrador 6
Shepherd Dog - German 6
Pointing Dog - German Short-haired 4
Retriever - Golden 4

Associated Drugs

Fluralaner 13.64% 12-Week Chew 22
Gabapentin 16
Carprofen 14
Lotilaner 13
Doxycycline 12
Afoxolaner 12
Maropitant Citrate 12
Metronidazole 9
Bexagliflozin 9
Oclacitinib Maleate 7
Propofol 7
Enrofloxacin 7
Meloxicam 7
Milbemycin Oxime + Praziquantel 7
Dexmedetomidine 7
Prednisone 7
Dexamethasone Sodium Phosphate 6
Omeprazole 6
Maropitant 6
Buprenorphine 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Low pancreatic enzymes, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (127 here).

Similar death-coded share

Nearest other reactions by death-coded share (18.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Low pancreatic enzymes (#1276 of 2,481 by report volume); death-coded 18.1%. PlainBreed reaction plate · death-coded share stamp 18.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →