Reaction profile

The FDA adverse-event record for generalised skin slough

29 FDA reports name generalised skin slough, a lower-volume reaction in the CVM extract (VeDDRA 943). Plate stamps and neighbourhood peers follow.

#2013 of 2,481
by report volume (all reactions)
29
reports citing this reaction
6.9%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Generalised skin slough has 29 reports now versus 27 in that prior snapshot: 2 more (7.4%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Generalised skin slough changes

FDA AER · VeDDRA plate

Code 943 VOL-TRACE

VOL-TRACE · DEATH-PAR · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 29 reports
  • DEATH-PAR 6.9%
  • LOWER-Q #2013/2481
  • PHOTO-FINISH Application site mois…
  • SPECIES-DOG Dog · 22
  • DRUG-LEAD Unspecified · 11
  • DESK-WIDE 18 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site moist eczema (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Generalised skin slough

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site mois… · near29Blue eye · near29Enteric pathogen NOS · near29Generalised skin slou… · thi…29Lack of efficacy (bac… · near29Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Generalised skin slough

Generalised skin slough: low death-coded share in the FDA AER plate

Signature read: 2 death-coded reports is a thin tail count for Generalised skin slough in the CVM extract. Report volume is lower-third scale: 29 named reports in the openFDA extract. Death-coded share is lower-third: 2 of 29 reports (6.9% of named reports). Nearest volume peer: Application site moist eczema (±0 reports). Lead species Dog (22). Lead co-reported drug Unspecified (11).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Unspecified appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 22
Cat 6
Horse 1

Breeds Most Affected

Retriever - Labrador 4
Dog (unknown) 3
Shepherd Dog - Australian 3
Domestic Shorthair 3
Rottweiler 2
Dachshund (unspecified) 2
Hound (unspecified) 1
Terrier - Boston 1
Terrier (unspecified) 1
Cat (unknown) 1

Associated Drugs

Unspecified 11
Tigilanol Tiglate 7
Diphenhydramine 7
Carprofen 6
Prednisone 6
Cefovecin 5
Gabapentin 5
Butorphanol 4
Famotidine 4
Atipamezole 4
Enrofloxacin 4
Dexmedetomidine 3
Alfaxalone 3
Robenacoxib 3
Maropitant Citrate 3
Dexmedetomidine Hydrochloride 2
Grapiprant 2
Rabies Virus, Kv 2
Nystatin, Neomycin Sulfate, Thiostrepton, And Triamcinolone 2
Bedinvetmab 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Generalised skin slough (#2013 of 2,481 by report volume); death-coded 6.9%. PlainBreed reaction plate · death-coded report count stamp 2 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →