Reaction profile

The FDA adverse-event record for retinal disorder nos

223 FDA adverse-event reports reference retinal disorder nos (VeDDRA 466). See the species, breeds, and drugs most associated with it below.

223
reports citing this reaction
14.3%
death-coded share
Dog
most-affected species
Enrofloxacin
most-associated drug
Verify with FDA CVM →
223
Total Reports
32
Deaths
14.3%
Death Rate

Species Most Affected

Dog 146
Cat 76
Horse 1

Breeds Most Affected

Domestic Shorthair 32
Domestic (unspecified) 28
Retriever - Labrador 12
Crossbred Canine/dog 11
Dachshund (unspecified) 10
Cat (unknown) 7
Retriever - Golden 7
Shih Tzu 7
Chihuahua 6
Dog (unknown) 6

Associated Drugs

Enrofloxacin 21
Spinosad 21
Milbemycin Oxime + Spinosad 20
Fluralaner Chew Tablets 16
Ivermectin 13
Doxycycline 13
Moxidectin 10
Ivermectin + Pyrantel As Pamoate Salt 10
Orbifloxacin 9
Orbifloxacin Oral Suspension 9
Dirlotapide 8
Afoxolaner 8
Fluralaner 13.64% 12-Week Chew 8
Carprofen 7
Cefovecin Sodium 7
Marbofloxacin 7
Selamectin 6
Prednisolone 6
Maropitant Citrate 6
Meloxicam 5

Retinal disorder NOS Reaction Insights

223 reports name Retinal disorder NOS; 32 recorded a death outcome (14.3% of reported events, not a population-level mortality rate). VeDDRA code: 466.

By species: Dog (146 reports), Cat (76 reports), Horse (1 reports). By breed: Domestic Shorthair (32), Domestic (unspecified) (28), Retriever - Labrador (12).

Most co-reported drugs: Enrofloxacin (21 reports), Spinosad (21 reports), Milbemycin Oxime + Spinosad (20 reports), Fluralaner Chew Tablets (16 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.