Reaction profile

The FDA adverse-event record for abnormal schirmer tear test

47 FDA adverse-event reports reference abnormal schirmer tear test (VeDDRA 2666). See the species, breeds, and drugs most associated with it below.

47
reports citing this reaction
4.3%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
47
Total Reports
2
Deaths
4.3%
Death Rate

Species Most Affected

Dog 47

Breeds Most Affected

Poodle - Miniature 5
Retriever - Labrador 4
Terrier - Yorkshire 4
Maltese 4
Chihuahua 4
Shih Tzu 4
Dachshund (unspecified) 3
Spaniel - King Charles Cavalier 2
Crossbred Canine/dog 2
Bulldog - French 2

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 27
Maropitant Citrate 16
Prednisone 13
Cyclosporine (Ophthalmic) 12
Gabapentin 11
Pilocarpine 10
Fluid Therapy 8
Anti-Il31 Mab Mcs Lot #1283563 6
Enrofloxacin 6
Ofloxacin 6
Tobramycin 6
Bacitracin + Neomycin + Polymyxin B 6
Moxidectin 5
Cyclosporine 5
Carprofen 5
Florfenicol, Terbinafine Hcl, Mometasone Furoate 5
Lokivetmab Injectable Solution 5
Carprofen (Unknown) 5
Midazolam 5
Pilocarpine Ophthalmic 5

Abnormal Schirmer tear test Reaction Insights

47 reports name Abnormal Schirmer tear test; 2 recorded a death outcome (4.3% of reported events, not a population-level mortality rate). VeDDRA code: 2666.

By species: Dog (47 reports). By breed: Poodle - Miniature (5), Retriever - Labrador (4), Terrier - Yorkshire (4).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (27 reports), Maropitant Citrate (16 reports), Prednisone (13 reports), Cyclosporine (Ophthalmic) (12 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.