Reaction profile

The FDA adverse-event record for duodenitis

Name: Duodenitis - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

38 FDA reports name duodenitis, a lower-volume reaction in the CVM extract (VeDDRA 325). Plate stamps and neighbourhood peers follow.

#1871 of 2,481
by report volume (all reactions): 38
reports citing this reaction: 60.5%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Duodenitis has 38 reports now versus 37 in that prior snapshot: 1 more (2.7%).

Report change: +1
Death-coded reports: +1
Death-coded share: +1.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Duodenitis changes

FDA AER · VeDDRA plate

Code 325 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 38 reports
DEATH-HOT 60.5%
LOWER-Q #1871/2481
PHOTO-FINISH Clenched jaw
SPECIES-DOG Dog · 34
DRUG-LEAD Ondansetron · 8
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Clenched jaw (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Duodenitis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Duodenitis

Duodenitis: high death-coded share in the FDA AER plate

Signature read: Duodenitis's 60.5% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 38 named reports in the openFDA extract. Death-coded share is upper-third: 23 of 38 reports (60.5% of named reports). Nearest volume peer: Clenched jaw (±0 reports). Lead species Dog (34). Lead co-reported drug Ondansetron (8).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 34

Cattle 2

Horse 1

Cat 1

Breeds Most Affected

Retriever - Labrador 12

Retriever - Golden 3

Crossbred Canine/dog 2

Spaniel - Cocker American 2

Holstein-Friesian also known as Holstein 2

Spitz - Dutch (Keeshond) 1

Dalmatian 1

Spaniel - Cocker English 1

Terrier - West Highland White 1

Boxer (German Boxer) 1

Associated Drugs

Ondansetron 8

Maropitant Citrate 7

Carprofen 7

Deracoxib 6

Buprenorphine 6

Propofol 6

Midazolam 6

Grapiprant 5

Gabapentin 5

Hydromorphone 5

Acetaminophen 4

Omeprazole 4

Trazodone 4

Maropitant 4

Atropine 4

Ketamine 4

Milbemycin Oxime + Spinosad 3

Firocoxib 3

Afoxolaner, Moxidectin, Pyrantel 3

Meloxicam 3

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Duodenitis (#1871 of 2,481 by report volume); death-coded 60.5%. PlainBreed reaction plate · death-coded share stamp 60.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →