PR-PANCREAS, LESION(S)

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VeDDRA Code: 99658

147 adverse event reports referencing this reaction

147
Total Reports
138
Deaths
9390.0%
Death Rate

Species Most Affected

Dog 88
Cat 58
Cattle 1

Breeds Most Affected

Domestic (unspecified) 21
Domestic Shorthair 16
Retriever - Labrador 14
Crossbred Canine/dog 12
Persian 5
Domestic Mediumhair 5
Terrier - Yorkshire 5
Boxer (German Boxer) 4
Retriever - Golden 4
Pinscher - Miniature 4

Associated Drugs

Carprofen 12
Cefovecin Sodium 11
Maropitant Citrate 11
Cefovecin 11
Maropitant 9
Deracoxib 8
Moxidectin 8
Milbemycin Oxime + Spinosad 8
Fluralaner Chew Tablets 8
Spinosad 7
Meloxicam 6
Trilostane 5
Robenacoxib 5
Enrofloxacin 5
Toceranib Phosphate 4
Dexmedetomidine Hydrochloride 4
Tramadol 4
Famotidine 4
Buprenorphine 4
Firocoxib 3

Data Summary

Metric Value
Total reports referencing reaction 147
Reports with fatal outcome 138
Case-fatality rate (reported events) 9390.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99658.

PR-PANCREAS, LESION(S) Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 147 adverse event reports that reference PR-PANCREAS, LESION(S) as a reaction term, including 138 reports with a death outcome — a 9390.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99658, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

PR-PANCREAS, LESION(S) appears most frequently in reports for Dog (88 reports), Cat (58 reports), Cattle (1 reports) — with Dog dominating at 88 entries. Within those species, the breeds most often named alongside this reaction are Domestic (unspecified) (21), Domestic Shorthair (16), Retriever - Labrador (14). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with PR-PANCREAS, LESION(S) are Carprofen (12 reports), Cefovecin Sodium (11 reports), Maropitant Citrate (11 reports), Cefovecin (11 reports), with Carprofen appearing alongside this reaction in 12 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial