Reaction profile

The FDA adverse-event record for other metabolic disorder

35 FDA reports name other metabolic disorder, a lower-volume reaction in the CVM extract (VeDDRA 1668). Plate stamps and neighbourhood peers follow.

#1924 of 2,481
by report volume (all reactions)
35
reports citing this reaction
25.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Other metabolic disorder has 35 reports now versus 34 in that prior snapshot: 1 more (2.9%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.8 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Other metabolic disorder changes

FDA AER · VeDDRA plate

Code 1668 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 35 reports
  • DEATH-HOT 25.7%
  • LOWER-Q #1924/2481
  • PHOTO-FINISH CARBON DIOXIDE LOW, B…
  • SPECIES-DOG Dog · 16
  • DRUG-LEAD Monensin Sodium · 6
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: CARBON DIOXIDE LOW, BLOOD (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Other metabolic disorder

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348CARBON DIOXIDE LOW, B… · near35Cerebral oedema · near35Comedo/blackhead · near35Gastric torsion · near35Other metabolic disor… · thi…35Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Other metabolic disorder

Other metabolic disorder: high death-coded share in the FDA AER plate

Signature read: 35 reports place Other metabolic disorder in the lower third of FDA AER volume (#1924 of 2,481). Report volume is lower-third scale: 35 named reports in the openFDA extract. Death-coded share is upper-third: 9 of 35 reports (25.7% of named reports). Nearest volume peer: CARBON DIOXIDE LOW, BLOOD (±0 reports). Lead species Dog (16). Lead co-reported drug Monensin Sodium (6).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 16
Cat 8
Horse 4
Goat 3
Cattle 2
Turkey 2

Breeds Most Affected

Domestic Shorthair 5
Retriever - Labrador 4
Boer 3
Turkey (unknown) 2
Unknown 1
Spaniel - King Charles Cavalier 1
Holstein-Friesian also known as Holstein 1
Dachshund - Standard Smooth-haired 1
Shepherd Dog - German 1
Doberman Pinscher 1

Associated Drugs

Monensin Sodium 6
Milbemycin Oxime + Spinosad 4
Ivermectin + Pyrantel As Pamoate Salt 4
Bexagliflozin 4
Afoxolaner 2
Trenbolone Acet/Estrad Sr Imp 2
Prednisone 2
Pergolide Mesylate 2
Prescription Diet 2
Metronidazole 2
Pyrantel 1
Pain Meds (Unknown) 1
Sometribove 1
Trilostane 1
Tramadol 1
Afoxolaner 136 Mg Chewable Tablets 1
Imidacloprid/Moxidectin 1
Milbemycin Oxime/Praziquantel 1
Deracoxib 1
Fatty Acid/Fish Oil Supplement 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Other metabolic disorder (#1924 of 2,481 by report volume); death-coded 25.7%. PlainBreed reaction plate · report volume stamp 35 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →