Reaction profile

The FDA adverse-event record for other metabolic disorder

34 FDA adverse-event reports reference other metabolic disorder (VeDDRA 1668). See the species, breeds, and drugs most associated with it below.

34
reports citing this reaction
26.5%
death-coded share
Dog
most-affected species
Monensin Sodium
most-associated drug
Verify with FDA CVM →
34
Total Reports
9
Deaths
26.5%
Death Rate

Species Most Affected

Dog 16
Cat 7
Horse 4
Goat 3
Cattle 2
Turkey 2

Breeds Most Affected

Retriever - Labrador 4
Domestic Shorthair 4
Boer 3
Turkey (unknown) 2
Unknown 1
Spaniel - King Charles Cavalier 1
Dachshund - Standard Smooth-haired 1
Holstein-Friesian also known as Holstein 1
Shepherd Dog - German 1
Doberman Pinscher 1

Associated Drugs

Monensin Sodium 6
Milbemycin Oxime + Spinosad 4
Ivermectin + Pyrantel As Pamoate Salt 4
Bexagliflozin 4
Afoxolaner 2
Trenbolone Acet/Estrad Sr Imp 2
Prednisone 2
Pergolide Mesylate 2
Metronidazole 2
Prescription Diet 2
Pyrantel 1
Pain Meds (Unknown) 1
Trilostane 1
Tramadol 1
Sometribove 1
Afoxolaner 136 Mg Chewable Tablets 1
Imidacloprid/Moxidectin 1
Milbemycin Oxime/Praziquantel 1
Deracoxib 1
Fatty Acid/Fish Oil Supplement 1

Other metabolic disorder Reaction Insights

34 reports name Other metabolic disorder; 9 recorded a death outcome (26.5% of reported events, not a population-level mortality rate). VeDDRA code: 1668.

By species: Dog (16 reports), Cat (7 reports), Horse (4 reports). By breed: Retriever - Labrador (4), Domestic Shorthair (4), Boer (3).

Most co-reported drugs: Monensin Sodium (6 reports), Milbemycin Oxime + Spinosad (4 reports), Ivermectin + Pyrantel As Pamoate Salt (4 reports), Bexagliflozin (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.