Reaction profile

The FDA adverse-event record for licking

2,506 FDA reports name licking, a high-volume reaction in the CVM extract (VeDDRA 1997). Plate stamps and neighbourhood peers follow.

#189 of 2,481
by report volume (all reactions)
2,506
reports citing this reaction
2.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Licking has 2,506 reports now versus 2,457 in that prior snapshot: 49 more (2.0%).

Report change
+49
Death-coded reports
+1
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Licking changes

FDA AER · VeDDRA plate

Code 1997 VOL-MID

VOL-MID · DEATH-LOW · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,506 reports
  • DEATH-LOW 2.6%
  • TOP-DECILE #189/2481
  • PHOTO-FINISH Vials, Damaged
  • SPECIES-DOG Dog · 1,765
  • DRUG-LEAD Nitenpyram · 253
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Vials, Damaged (±6 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Licking

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Licking · this reaction2506Vials, Damaged · near2500Elevated aspartate am… · near2499Nystagmus · near2489Head tremor · near2485Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Licking

Licking: low death-coded share in the FDA AER plate

Signature read: 2,506 reports place Licking in the upper third of FDA AER volume (#189 of 2,481). Report volume is upper-third scale: 2,506 named reports in the openFDA extract. Death-coded share is lower-third: 65 of 2,506 reports (2.6% of named reports). Nearest volume peer: Vials, Damaged (±6 reports). Lead species Dog (1,765). Lead co-reported drug Nitenpyram (253).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Nitenpyram appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,765
Cat 696
Cattle 43
Horse 2

Breeds Most Affected

Domestic Shorthair 417
Retriever - Labrador 191
Crossbred Canine/dog 155
Retriever - Golden 85
Shepherd Dog - German 79
Domestic Longhair 77
Dog (unknown) 67
Terrier - Yorkshire 61
Shih Tzu 58
Chihuahua 57

Associated Drugs

Nitenpyram 253
Milbemycin Oxime + Spinosad 242
Afoxolaner 208
Oclacitinib Maleate 159
Carprofen 123
Ivermectin + Pyrantel As Pamoate Salt 103
Fluralaner Chew Tablets 102
Milbemycin Oxime + Praziquantel 102
Spinosad 96
Selamectin 92
Bedinvetmab 86
Gabapentin 83
Lotilaner 80
Trilostane 77
Fluralaner Spot-On Solution 77
Pyrantel Pamoate;Sarolaner 69
Imidacloprid + Moxidectin 66
Frunevetmab 66
Fluralaner 13.64% 12-Week Chew 61
Moxidectin 51

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Licking, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (2,506 here).

Similar death-coded share

Nearest other reactions by death-coded share (2.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Licking (#189 of 2,481 by report volume); death-coded 2.6%. PlainBreed reaction plate · report volume stamp 2,506 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →