Reaction profile

The FDA adverse-event record for licking

2,385 FDA adverse-event reports reference licking (VeDDRA 1997). See the species, breeds, and drugs most associated with it below.

2,385
reports citing this reaction
2.6%
death-coded share
Dog
most-affected species
Nitenpyram
most-associated drug
Verify with FDA CVM →
2,385
Total Reports
62
Deaths
2.6%
Death Rate

Species Most Affected

Dog 1,672
Cat 668
Cattle 42
Horse 2
Goat 1

Breeds Most Affected

Domestic Shorthair 404
Retriever - Labrador 181
Crossbred Canine/dog 145
Retriever - Golden 83
Domestic Longhair 75
Shepherd Dog - German 71
Dog (unknown) 66
Terrier - Yorkshire 61
Chihuahua 56
Shih Tzu 54

Associated Drugs

Nitenpyram 248
Milbemycin Oxime + Spinosad 240
Afoxolaner 204
Oclacitinib Maleate 142
Carprofen 116
Ivermectin + Pyrantel As Pamoate Salt 103
Fluralaner Chew Tablets 102
Spinosad 96
Milbemycin Oxime + Praziquantel 95
Selamectin 87
Bedinvetmab 79
Trilostane 76
Fluralaner Spot-On Solution 76
Gabapentin 73
Lotilaner 67
Imidacloprid + Moxidectin 65
Pyrantel Pamoate;Sarolaner 63
Frunevetmab 58
Fluralaner 13.64% 12-Week Chew 57
Moxidectin 47

Licking Reaction Insights

2,385 reports name Licking; 62 recorded a death outcome (2.6% of reported events, not a population-level mortality rate). VeDDRA code: 1997.

By species: Dog (1,672 reports), Cat (668 reports), Cattle (42 reports). By breed: Domestic Shorthair (404), Retriever - Labrador (181), Crossbred Canine/dog (145).

Most co-reported drugs: Nitenpyram (248 reports), Milbemycin Oxime + Spinosad (240 reports), Afoxolaner (204 reports), Oclacitinib Maleate (142 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.