Licking

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VeDDRA Code: 1997

2,385 adverse event reports referencing this reaction

2,385
Total Reports
62
Deaths
260.0%
Death Rate

Species Most Affected

Dog 1,672
Cat 668
Cattle 42
Horse 2
Goat 1

Breeds Most Affected

Domestic Shorthair 404
Retriever - Labrador 181
Crossbred Canine/dog 145
Retriever - Golden 83
Domestic Longhair 75
Shepherd Dog - German 71
Dog (unknown) 66
Terrier - Yorkshire 61
Chihuahua 56
Shih Tzu 54

Associated Drugs

Nitenpyram 248
Milbemycin Oxime + Spinosad 240
Afoxolaner 204
Oclacitinib Maleate 142
Carprofen 116
Ivermectin + Pyrantel As Pamoate Salt 103
Fluralaner Chew Tablets 102
Spinosad 96
Milbemycin Oxime + Praziquantel 95
Selamectin 87
Bedinvetmab 79
Trilostane 76
Fluralaner Spot-On Solution 76
Gabapentin 73
Lotilaner 67
Imidacloprid + Moxidectin 65
Pyrantel Pamoate;Sarolaner 63
Frunevetmab 58
Fluralaner 13.64% 12-Week Chew 57
Moxidectin 47

Data Summary

Metric Value
Total reports referencing reaction 2,385
Reports with fatal outcome 62
Case-fatality rate (reported events) 260.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1997.

Licking Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 2,385 adverse event reports that reference Licking as a reaction term, including 62 reports with a death outcome — a 260.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1997, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Licking appears most frequently in reports for Dog (1,672 reports), Cat (668 reports), Cattle (42 reports) — with Dog dominating at 1,672 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (404), Retriever - Labrador (181), Crossbred Canine/dog (145). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Licking are Nitenpyram (248 reports), Milbemycin Oxime + Spinosad (240 reports), Afoxolaner (204 reports), Oclacitinib Maleate (142 reports), with Nitenpyram appearing alongside this reaction in 248 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial