Reaction profile

The FDA adverse-event record for complication of diabetes

16 FDA adverse-event reports reference complication of diabetes (VeDDRA 393). See the species, breeds, and drugs most associated with it below.

16
reports citing this reaction
31.3%
death-coded share
Dog
most-affected species
Insulin Injectable Vial
most-associated drug
Verify with FDA CVM →
16
Total Reports
5
Deaths
31.3%
Death Rate

Species Most Affected

Dog 13
Cat 3

Breeds Most Affected

Domestic Shorthair 3
Retriever - Labrador 3
Dog (unknown) 3
Crossbred Canine/dog 2
Dachshund (unspecified) 1
Shih Tzu 1
Terrier - West Highland White 1
Pinscher - Miniature 1
Terrier - Bull - American Pit 1

Associated Drugs

Insulin Injectable Vial 6
Trilostane 3
Insulin 2
Ivermectin 68Mcg Pyrantel 57Mg 1
Recombinant Human Insulin 1
Prednisolone 1
Telmisartan 1
Meloxicam 1
Gabapentin 1
Glucosamine 1
Vitamin D Supplement 1
Fluralaner Chew Tablets 1
Spinosad 1
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 1
Cefovecin 1
Regular Insulin 1
Milbemycin Oxime + Spinosad 1
Bedinvetmab 1

Complication of diabetes Reaction Insights

16 reports name Complication of diabetes; 5 recorded a death outcome (31.3% of reported events, not a population-level mortality rate). VeDDRA code: 393.

By species: Dog (13 reports), Cat (3 reports). By breed: Domestic Shorthair (3), Retriever - Labrador (3), Dog (unknown) (3).

Most co-reported drugs: Insulin Injectable Vial (6 reports), Trilostane (3 reports), Insulin (2 reports), Ivermectin 68Mcg Pyrantel 57Mg (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.