Reaction profile

The FDA adverse-event record for inversion of albumin/globulin ratio

65 FDA adverse-event reports reference inversion of albumin/globulin ratio (VeDDRA 2117). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1612 of 2,481
by report volume (all reactions)
65
reports citing this reaction
24.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Inversion of albumin/globulin ratio has 65 reports now versus 60 in that prior snapshot: 5 more (8.3%).

Report change
+5
Death-coded reports
+1
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Inversion of albumin/globulin ratio changes

FDA AER · VeDDRA plate

Code 2117 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 65 reports
  • DEATH-HOT 24.6%
  • MID-PACK #1612/2481
  • PHOTO-FINISH Acne
  • SPECIES-DOG Dog · 54
  • DRUG-LEAD Carprofen · 8
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Acne (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Inversion of albumin/globulin ratio

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Acne · near65Gut sounds decreased · near65Hair standing on end · near65Immune-mediated polya… · near65Inversion of albumin/… · thi…65Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Inversion of albumin/globulin ratio

Inversion of albumin/globulin ratio: high death-coded share in the FDA AER plate

Signature read: Inversion of albumin/globulin ratio's 24.6% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 16 of 65 reports (24.6% of named reports). Nearest volume peer: Acne (±0 reports). Lead species Dog (54). Lead co-reported drug Carprofen (8).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 54
Cat 5
Cattle 3
Horse 3

Breeds Most Affected

Retriever - Labrador 7
Crossbred Canine/dog 6
Pit Bull 3
Shih Tzu 3
Domestic Shorthair 3
Spaniel - Cocker American 2
Beagle 2
Poodle (unspecified) 2
Deutsche Dogge, Great Dane 2
Poodle - Standard 2

Associated Drugs

Carprofen 8
Fluralaner Chew Tablets 8
Maropitant Citrate 7
Gabapentin 6
Ilunocitinib 6
Spinosad 5
Milbemycin Oxime + Spinosad 4
Fluid Therapy 4
Prednisone 3
Prednisolone 3
Milbemycin Oxime + Praziquantel 3
Grapiprant 3
Bedinvetmab 3
Fluralaner 13.64% 12-Week Chew 3
Meloxicam 2
Rabies Vaccine 2
Trilostane 2
Oclacitinib Maleate 2
Deracoxib 2
Fluralaner 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Inversion of albumin/globulin ratio, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (65 here).

Similar death-coded share

Nearest other reactions by death-coded share (24.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Inversion of albumin/globulin ratio (#1612 of 2,481 by report volume); death-coded 24.6%. PlainBreed reaction plate · death-coded share stamp 24.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →