Tachycardia

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VeDDRA Code: 192

4,476 adverse event reports referencing this reaction

4,476
Total Reports
1,049
Deaths
2340.0%
Death Rate

Species Most Affected

Dog 3,454
Cat 747
Horse 202
Human 44
Cattle 12
Rabbit 5
Guinea Pig 2
Donkey 2
Other Equids 2
Other 1

Breeds Most Affected

Domestic Shorthair 401
Retriever - Labrador 400
Crossbred Canine/dog 268
Shepherd Dog - German 132
Chihuahua 132
Retriever - Golden 127
Boxer (German Boxer) 117
Terrier - Yorkshire 108
Dog (unknown) 104
Domestic (unspecified) 101

Associated Drugs

Moxidectin 514
Maropitant Citrate 337
Carprofen 309
Milbemycin Oxime + Spinosad 214
Buprenorphine 178
Isoflurane 174
Propofol 163
Butorphanol 157
Dexmedetomidine Hydrochloride 149
Oclacitinib Maleate 147
Afoxolaner 146
Deracoxib 145
Melarsomine Dihydrochloride 144
Gabapentin 144
Spinosad 115
Bedinvetmab 113
Pimobendan 109
Dexamethasone 105
Prednisone 104
Selamectin 103

Data Summary

Metric Value
Total reports referencing reaction 4,476
Reports with fatal outcome 1,049
Case-fatality rate (reported events) 2340.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 192.

Tachycardia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 4,476 adverse event reports that reference Tachycardia as a reaction term, including 1,049 reports with a death outcome — a 2340.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 192, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Tachycardia appears most frequently in reports for Dog (3,454 reports), Cat (747 reports), Horse (202 reports) — with Dog dominating at 3,454 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (401), Retriever - Labrador (400), Crossbred Canine/dog (268). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Tachycardia are Moxidectin (514 reports), Maropitant Citrate (337 reports), Carprofen (309 reports), Milbemycin Oxime + Spinosad (214 reports), with Moxidectin appearing alongside this reaction in 514 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial