Dehiscence

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VeDDRA Code: 2080

122 adverse event reports referencing this reaction

122
Total Reports
25
Deaths
2050.0%
Death Rate

Species Most Affected

Dog 87
Cat 26
Unknown 3
Horse 3
Cattle 2
Guinea Pig 1

Breeds Most Affected

Domestic Shorthair 19
Retriever - Labrador 14
Retriever - Golden 5
Boxer (German Boxer) 5
Dog (unknown) 4
Shepherd Dog - German 4
Shih Tzu 4
Unknown 4
Rottweiler 4
Terrier - Bull - American Pit 3

Associated Drugs

Carprofen 26
Isoflurane 21
Maropitant Citrate 20
Buprenorphine 20
Robenacoxib 17
Bupivacaine 16
Propofol 14
Dexmedetomidine 12
Gabapentin 12
Deracoxib 11
Hydromorphone 11
Ketamine 10
Oclacitinib Maleate 9
Midazolam 9
Enrofloxacin 8
Cefovecin 8
Meloxicam 6
Cefpodoxime Proxetil 6
Acepromazine 6
Anesthetic 5

Data Summary

Metric Value
Total reports referencing reaction 122
Reports with fatal outcome 25
Case-fatality rate (reported events) 2050.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2080.

Dehiscence Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 122 adverse event reports that reference Dehiscence as a reaction term, including 25 reports with a death outcome — a 2050.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2080, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Dehiscence appears most frequently in reports for Dog (87 reports), Cat (26 reports), Unknown (3 reports) — with Dog dominating at 87 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (19), Retriever - Labrador (14), Retriever - Golden (5). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Dehiscence are Carprofen (26 reports), Isoflurane (21 reports), Maropitant Citrate (20 reports), Buprenorphine (20 reports), with Carprofen appearing alongside this reaction in 26 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial