Reaction profile

The FDA adverse-event record for dehiscence

122 FDA adverse-event reports reference dehiscence (VeDDRA 2080). See the species, breeds, and drugs most associated with it below.

122
reports citing this reaction
20.5%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
122
Total Reports
25
Deaths
20.5%
Death Rate

Species Most Affected

Dog 87
Cat 26
Unknown 3
Horse 3
Cattle 2
Guinea Pig 1

Breeds Most Affected

Domestic Shorthair 19
Retriever - Labrador 14
Retriever - Golden 5
Boxer (German Boxer) 5
Dog (unknown) 4
Shepherd Dog - German 4
Shih Tzu 4
Unknown 4
Rottweiler 4
Terrier - Bull - American Pit 3

Associated Drugs

Carprofen 26
Isoflurane 21
Maropitant Citrate 20
Buprenorphine 20
Robenacoxib 17
Bupivacaine 16
Propofol 14
Dexmedetomidine 12
Gabapentin 12
Deracoxib 11
Hydromorphone 11
Ketamine 10
Oclacitinib Maleate 9
Midazolam 9
Enrofloxacin 8
Cefovecin 8
Meloxicam 6
Cefpodoxime Proxetil 6
Acepromazine 6
Anesthetic 5

Dehiscence Reaction Insights

122 reports name Dehiscence; 25 recorded a death outcome (20.5% of reported events, not a population-level mortality rate). VeDDRA code: 2080.

By species: Dog (87 reports), Cat (26 reports), Unknown (3 reports). By breed: Domestic Shorthair (19), Retriever - Labrador (14), Retriever - Golden (5).

Most co-reported drugs: Carprofen (26 reports), Isoflurane (21 reports), Maropitant Citrate (20 reports), Buprenorphine (20 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.