Reaction profile

The FDA adverse-event record for not eating

19,809 FDA adverse-event reports reference not eating (VeDDRA 1207). See the species, breeds, and drugs most associated with it below.

19,809
reports citing this reaction
15.3%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
19,809
Total Reports
3,027
Deaths
15.3%
Death Rate

Species Most Affected

Dog 15,354
Cat 4,043
Cattle 204
Horse 129
Pig 14
Turkey 11
Human 9
Chicken 7
Goat 7
Rabbit 5

Breeds Most Affected

Domestic Shorthair 2,420
Retriever - Labrador 1,450
Crossbred Canine/dog 1,107
Chihuahua 833
Terrier - Yorkshire 680
Retriever - Golden 667
Shih Tzu 597
Shepherd Dog - German 503
Boxer (German Boxer) 464
Dog (unknown) 445

Associated Drugs

Milbemycin Oxime + Spinosad 2,814
Afoxolaner 1,482
Maropitant Citrate 1,246
Carprofen 1,096
Bedinvetmab 903
Ivermectin + Pyrantel As Pamoate Salt 875
Pyrantel Pamoate;Sarolaner 850
Gabapentin 798
Spinosad 796
Buprenorphine 748
Milbemycin Oxime + Praziquantel 731
Fluralaner 13.64% 12-Week Chew 606
Moxidectin 595
Fluralaner Chew Tablets 550
Cefovecin 539
Oclacitinib Maleate 533
Trilostane 530
Prednisone 475
Grapiprant 450
Lotilaner 416

Not eating Reaction Insights

19,809 reports name Not eating; 3,027 recorded a death outcome (15.3% of reported events, not a population-level mortality rate). VeDDRA code: 1207.

By species: Dog (15,354 reports), Cat (4,043 reports), Cattle (204 reports). By breed: Domestic Shorthair (2,420), Retriever - Labrador (1,450), Crossbred Canine/dog (1,107).

Most co-reported drugs: Milbemycin Oxime + Spinosad (2,814 reports), Afoxolaner (1,482 reports), Maropitant Citrate (1,246 reports), Carprofen (1,096 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.