Reaction profile

The FDA adverse-event record for not eating

21,007 FDA reports name not eating, a high-volume reaction in the CVM extract (VeDDRA 1207). Plate stamps and neighbourhood peers follow.

#19 of 2,481
by report volume (all reactions)
21,007
reports citing this reaction
15.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Not eating has 21,007 reports now versus 20,518 in that prior snapshot: 489 more (2.4%).

Report change
+489
Death-coded reports
+76
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Not eating changes

FDA AER · VeDDRA plate

Code 1207 VOL-HIGH

VOL-HIGH · DEATH-ELEV · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-HIGH 21,007 reports
  • DEATH-ELEV 15.4%
  • TOP-DECILE #19/2481
  • PHOTO-FINISH Death by euthanasia
  • SPECIES-DOG Dog · 16,145
  • DRUG-LEAD Milbemycin Oxime… · 2,820
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Death by euthanasia (±27 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Not eating

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Digestive tract disor… · near22748Ataxia · near21626Other abnormal test r… · near21162Death by euthanasia · near21034Not eating · this reaction21007Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Not eating

What the FDA AER plate says about Not eating

Signature read: 3,236 death-coded reports is a heavy tail count for Not eating in the CVM extract. Report volume is upper-third scale: 21,007 named reports in the openFDA extract. 3,236 of 21,007 reports were death-coded (15.4% of named reports, not a population mortality rate). Nearest volume peer: Death by euthanasia (±27 reports). Lead species Dog (16,145). Lead co-reported drug Milbemycin Oxime + Spinosad (2,820).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 16,145
Cat 4,430
Cattle 204
Horse 146
Pig 14
Turkey 11
Human 9
Goat 8
Chicken 7
Rabbit 6

Breeds Most Affected

Domestic Shorthair 2,685
Retriever - Labrador 1,533
Crossbred Canine/dog 1,164
Chihuahua 870
Terrier - Yorkshire 716
Retriever - Golden 708
Shih Tzu 621
Shepherd Dog - German 538
Boxer (German Boxer) 481
Dog (unknown) 460

Associated Drugs

Milbemycin Oxime + Spinosad 2,820
Afoxolaner 1,518
Maropitant Citrate 1,439
Carprofen 1,195
Bedinvetmab 1,042
Pyrantel Pamoate;Sarolaner 938
Gabapentin 902
Ivermectin + Pyrantel As Pamoate Salt 893
Buprenorphine 838
Spinosad 796
Milbemycin Oxime + Praziquantel 748
Moxidectin 642
Fluralaner 13.64% 12-Week Chew 635
Oclacitinib Maleate 577
Trilostane 575
Cefovecin 574
Fluralaner Chew Tablets 550
Prednisone 512
Grapiprant 482
Lotilaner 453

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Not eating, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (15.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Not eating (#19 of 2,481 by report volume); death-coded 15.4%. PlainBreed reaction plate · death-coded report count stamp 3,236 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →