Reaction profile

The FDA adverse-event record for coagulopathy

412 FDA reports name coagulopathy, a high-volume reaction in the CVM extract (VeDDRA 1057). Plate stamps and neighbourhood peers follow.

#714 of 2,481
by report volume (all reactions)
412
reports citing this reaction
46.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Coagulopathy has 412 reports now versus 409 in that prior snapshot: 3 more (0.7%).

Report change
+3
Death-coded reports
+1
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Coagulopathy changes

FDA AER · VeDDRA plate

Code 1057 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 412 reports
  • DEATH-HOT 46.4%
  • MID-PACK #714/2481
  • PHOTO-FINISH Spasm
  • SPECIES-DOG Dog · 362
  • DRUG-LEAD Carprofen · 114
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Spasm (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Coagulopathy

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Allergic dermatitis · near414Incorrect storage of… · near414Spasm · near413Coagulopathy · this reaction412Rigidity · near410Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Coagulopathy

Coagulopathy: high death-coded share in the FDA AER plate

Signature read: 191 death-coded reports is a heavy tail count for Coagulopathy in the CVM extract. Report volume is upper-third scale: 412 named reports in the openFDA extract. Death-coded share is upper-third: 191 of 412 reports (46.4% of named reports). Nearest volume peer: Spasm (±1 reports). Lead species Dog (362). Lead co-reported drug Carprofen (114).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 362
Cat 48
Horse 2

Breeds Most Affected

Retriever - Labrador 84
Crossbred Canine/dog 47
Domestic (unspecified) 22
Retriever - Golden 18
Domestic Shorthair 15
Shepherd Dog - German 13
Terrier - Yorkshire 11
Dog (unknown) 9
Dachshund (unspecified) 9
Pug 7

Associated Drugs

Carprofen 114
Maropitant Citrate 35
Moxidectin 28
Deracoxib 22
Meloxicam 22
Maropitant 21
Spinosad 19
Cefovecin Sodium 18
Melarsomine Dihydrochloride 14
Firocoxib 14
Buprenorphine 14
Plasma 14
Famotidine 14
Vitamin K1 12
Cefovecin 12
Milbemycin Oxime + Spinosad 11
Gabapentin 11
Glycosaminoglycan Polysulfate 10
Dexmedetomidine Hydrochloride 9
Cefpodoxime Proxetil 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Coagulopathy, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (412 here).

Similar death-coded share

Nearest other reactions by death-coded share (46.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Coagulopathy (#714 of 2,481 by report volume); death-coded 46.4%. PlainBreed reaction plate · death-coded report count stamp 191 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →