Reaction profile

The FDA adverse-event record for coagulopathy

406 FDA adverse-event reports reference coagulopathy (VeDDRA 1057). See the species, breeds, and drugs most associated with it below.

406
reports citing this reaction
46.3%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
406
Total Reports
188
Deaths
46.3%
Death Rate

Species Most Affected

Dog 356
Cat 48
Horse 2

Breeds Most Affected

Retriever - Labrador 83
Crossbred Canine/dog 46
Domestic (unspecified) 22
Retriever - Golden 18
Domestic Shorthair 15
Shepherd Dog - German 13
Terrier - Yorkshire 11
Dog (unknown) 9
Dachshund (unspecified) 9
Pug 7

Associated Drugs

Carprofen 114
Maropitant Citrate 34
Moxidectin 26
Deracoxib 22
Meloxicam 21
Maropitant 20
Spinosad 19
Cefovecin Sodium 18
Melarsomine Dihydrochloride 14
Firocoxib 14
Buprenorphine 14
Famotidine 14
Plasma 14
Vitamin K1 12
Cefovecin 12
Milbemycin Oxime + Spinosad 11
Glycosaminoglycan Polysulfate 10
Dexmedetomidine Hydrochloride 9
Cefpodoxime Proxetil 8
Gabapentin 8

Coagulopathy Reaction Insights

406 reports name Coagulopathy; 188 recorded a death outcome (46.3% of reported events, not a population-level mortality rate). VeDDRA code: 1057.

By species: Dog (356 reports), Cat (48 reports), Horse (2 reports). By breed: Retriever - Labrador (83), Crossbred Canine/dog (46), Domestic (unspecified) (22).

Most co-reported drugs: Carprofen (114 reports), Maropitant Citrate (34 reports), Moxidectin (26 reports), Deracoxib (22 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.