Reaction profile

The FDA adverse-event record for horner's syndrome

548 FDA reports name horner's syndrome, a high-volume reaction in the CVM extract (VeDDRA 702). Plate stamps and neighbourhood peers follow.

#611 of 2,481
by report volume (all reactions)
548
reports citing this reaction
8.2%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Horner's syndrome has 548 reports now versus 534 in that prior snapshot: 14 more (2.6%).

Report change
+14
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Horner's syndrome changes

FDA AER · VeDDRA plate

Code 702 VOL-MID

VOL-MID · DEATH-PAR · UPPER-Q · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 548 reports
  • DEATH-PAR 8.2%
  • UPPER-Q #611/2481
  • PHOTO-FINISH Low blood urea nitrog…
  • SPECIES-CAT Cat · 309
  • DRUG-LEAD Florfenicol + Mom… · 159
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Low blood urea nitrogen (BUN) (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Horner's syndrome

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Fly biting behaviour · near550Increased borborygmus · near550Low blood urea nitrog… · near549Horner's syndrome · this rea…548Excoriation · near546Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Horner's syndrome

What the FDA AER plate says about Horner's syndrome

Signature read: 548 reports place Horner's syndrome in the upper third of FDA AER volume (#611 of 2,481). Report volume is upper-third scale: 548 named reports in the openFDA extract. 45 of 548 reports were death-coded (8.2% of named reports, not a population mortality rate). Nearest volume peer: Low blood urea nitrogen (BUN) (±1 reports). Lead species Cat (309). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (159).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 309
Dog 234
Horse 2
Ferret 2
Other 1

Breeds Most Affected

Domestic Shorthair 199
Retriever - Labrador 61
Retriever - Golden 27
Cat (unknown) 25
Domestic Mediumhair 16
Domestic Longhair 16
Crossbred Canine/dog 12
Boxer (German Boxer) 11
Domestic (unspecified) 9
Pit Bull 9

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 159
Betamethasone + Florfenicol + Terbinafine 43
Bedinvetmab 40
Maropitant Citrate 35
Florfenicol, Terbinafine, Betamethasone Acetate 33
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 32
Prednisone 24
Oclacitinib Maleate 22
Gabapentin 21
Trilostane 19
Ear Cleaner 19
Buprenorphine 18
Mirtazapine 17
Cefovecin 16
Prednisolone 16
Carprofen 14
Cefovecin Sodium 13
Milbemycin Oxime + Spinosad 13
Enrofloxacin 13
Rabies Vaccine 13

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Horner's syndrome, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (548 here).

Similar death-coded share

Nearest other reactions by death-coded share (8.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Horner's syndrome (#611 of 2,481 by report volume); death-coded 8.2%. PlainBreed reaction plate · report volume stamp 548 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →