Reaction profile

The FDA adverse-event record for elevated insulin

31 FDA adverse-event reports reference elevated insulin (VeDDRA 2545). See the species, breeds, and drugs most associated with it below.

31
reports citing this reaction
6.5%
death-coded share
Horse
most-affected species
Pergolide Mesylate
most-associated drug
Verify with FDA CVM →
31
Total Reports
2
Deaths
6.5%
Death Rate

Species Most Affected

Horse 23
Dog 7
Donkey 1

Breeds Most Affected

Horse (unknown) 6
Quarter Horse 5
Arab 3
Warmblood (unspecified) 2
Pony (unspecified) 2
Spaniel - Springer English 1
Rottweiler 1
Donkey (unknown) 1
Shih Tzu 1
Poodle - Toy 1

Associated Drugs

Pergolide Mesylate 19
Firocoxib 4
Insulin Injectable Vial 2
Capromorelin Tartrate 2
Xylazine 2
Oclacitinib Maleate 1
Anti-Il31 Mab Mcs Lot #1283563 1
Gentamicin, Mometasone Furoate, And Clotrimazole 1
Fluralaner Chew Tablets 1
Spinosad 1
Clodronate Disodium 1
Polysulfated Glycosaminoglycan 1
Dexamethasone 1
Hydroxyzine 1
Flunixin 1
Oxytetracycline 1
Doxycycline 1
Bute 1

Elevated insulin Reaction Insights

31 reports name Elevated insulin; 2 recorded a death outcome (6.5% of reported events, not a population-level mortality rate). VeDDRA code: 2545.

By species: Horse (23 reports), Dog (7 reports), Donkey (1 reports). By breed: Horse (unknown) (6), Quarter Horse (5), Arab (3).

Most co-reported drugs: Pergolide Mesylate (19 reports), Firocoxib (4 reports), Insulin Injectable Vial (2 reports), Capromorelin Tartrate (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.