Reaction profile

The FDA adverse-event record for elevated insulin

Name: Elevated insulin - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

32 FDA reports name elevated insulin, a lower-volume reaction in the CVM extract (VeDDRA 2545). Plate stamps and neighbourhood peers follow.

#1956 of 2,481
by report volume (all reactions): 32
reports citing this reaction: 6.3%
death-coded share: Horse
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Elevated insulin has 32 reports now versus 32 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Elevated insulin changes

FDA AER · VeDDRA plate

Code 2545 VOL-TRACE

VOL-TRACE · DEATH-PAR · LOWER-Q · PHOTO-FINISH · SPECIES-HORSE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 32 reports
DEATH-PAR 6.3%
LOWER-Q #1956/2481
PHOTO-FINISH ANION GAP HI, BLD
SPECIES-HORSE Horse · 24
DRUG-LEAD Pergolide Mesylate · 20
DESK-WIDE 19 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: ANION GAP HI, BLD (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Elevated insulin

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Elevated insulin

Elevated insulin: low death-coded share in the FDA AER plate

Signature read: 2 death-coded reports is a thin tail count for Elevated insulin in the CVM extract. Report volume is lower-third scale: 32 named reports in the openFDA extract. Death-coded share is lower-third: 2 of 32 reports (6.3% of named reports). Nearest volume peer: ANION GAP HI, BLD (±0 reports). Lead species Horse (24). Lead co-reported drug Pergolide Mesylate (20).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Pergolide Mesylate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Horse 24

Dog 7

Donkey 1

Breeds Most Affected

Horse (unknown) 6

Quarter Horse 5

Arab 3

Warmblood (unspecified) 2

Pony (unspecified) 2

Spaniel - Springer English 1

Rottweiler 1

Donkey (unknown) 1

Shih Tzu 1

Poodle - Toy 1

Associated Drugs

Pergolide Mesylate 20

Firocoxib 4

Insulin Injectable Vial 2

Capromorelin Tartrate 2

Xylazine 2

Oclacitinib Maleate 1

Anti-Il31 Mab Mcs Lot #1283563 1

Gentamicin, Mometasone Furoate, And Clotrimazole 1

Fluralaner Chew Tablets 1

Spinosad 1

Clodronate Disodium 1

Polysulfated Glycosaminoglycan 1

Dexamethasone 1

Hydroxyzine 1

Flunixin 1

Oxytetracycline 1

Doxycycline 1

Bute 1

Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Elevated insulin (#1956 of 2,481 by report volume); death-coded 6.3%. PlainBreed reaction plate · death-coded report count stamp 2 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →