Sinusitis

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VeDDRA Code: 872

41 adverse event reports referencing this reaction

41
Total Reports
12
Deaths
2930.0%
Death Rate

Species Most Affected

Dog 19
Cat 16
Human 5
Cattle 1

Breeds Most Affected

Unknown 5
Domestic (unspecified) 5
Domestic Shorthair 5
Pit Bull 2
Ragdoll 2
Boxer (German Boxer) 1
Dog (unknown) 1
Sheepdog - Old English 1
Terrier - Boston 1
Poodle (unspecified) 1

Associated Drugs

Milbemycin Oxime + Spinosad 6
Selamectin 4
Spinosad 3
Ivermectin 2
Carprofen 2
Cefovecin Sodium 2
Cyclosporine 2
Clindamycin 2
Prednisone 2
Oclacitinib Maleate 2
Maropitant Citrate 2
Maropitant 1
Meloxicam 1
Methylprednisolone Acetate 1
Device: Animal Care (Bowls, Crates, Etc) 1
Amoxicillin 1
Bacitracin Methylene Disalicylate 1
Oxytetracycline Hydrochloride 1
Bovine Rhinotracheitis-Bvd-Pi3-Rsv Vaccine, Modified Live Virus, Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid 1
Clostridium Chauvoei-Septicum-Novyi-Sordellii-Perfringens Types C & D Bacterin-Toxoid 1

Data Summary

Metric Value
Total reports referencing reaction 41
Reports with fatal outcome 12
Case-fatality rate (reported events) 2930.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 872.

Sinusitis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 41 adverse event reports that reference Sinusitis as a reaction term, including 12 reports with a death outcome — a 2930.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 872, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Sinusitis appears most frequently in reports for Dog (19 reports), Cat (16 reports), Human (5 reports) — with Dog dominating at 19 entries. Within those species, the breeds most often named alongside this reaction are Unknown (5), Domestic (unspecified) (5), Domestic Shorthair (5). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Sinusitis are Milbemycin Oxime + Spinosad (6 reports), Selamectin (4 reports), Spinosad (3 reports), Ivermectin (2 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 6 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial