Reaction profile

The FDA adverse-event record for sinusitis

41 FDA adverse-event reports reference sinusitis (VeDDRA 872). See the species, breeds, and drugs most associated with it below.

41
reports citing this reaction
29.3%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
41
Total Reports
12
Deaths
29.3%
Death Rate

Species Most Affected

Dog 19
Cat 16
Human 5
Cattle 1

Breeds Most Affected

Unknown 5
Domestic (unspecified) 5
Domestic Shorthair 5
Pit Bull 2
Ragdoll 2
Boxer (German Boxer) 1
Dog (unknown) 1
Sheepdog - Old English 1
Terrier - Boston 1
Poodle (unspecified) 1

Associated Drugs

Milbemycin Oxime + Spinosad 6
Selamectin 4
Spinosad 3
Ivermectin 2
Carprofen 2
Cefovecin Sodium 2
Cyclosporine 2
Clindamycin 2
Prednisone 2
Oclacitinib Maleate 2
Maropitant Citrate 2
Maropitant 1
Meloxicam 1
Methylprednisolone Acetate 1
Device: Animal Care (Bowls, Crates, Etc) 1
Amoxicillin 1
Bacitracin Methylene Disalicylate 1
Oxytetracycline Hydrochloride 1
Bovine Rhinotracheitis-Bvd-Pi3-Rsv Vaccine, Modified Live Virus, Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid 1
Clostridium Chauvoei-Septicum-Novyi-Sordellii-Perfringens Types C & D Bacterin-Toxoid 1

Sinusitis Reaction Insights

41 reports name Sinusitis; 12 recorded a death outcome (29.3% of reported events, not a population-level mortality rate). VeDDRA code: 872.

By species: Dog (19 reports), Cat (16 reports), Human (5 reports). By breed: Unknown (5), Domestic (unspecified) (5), Domestic Shorthair (5).

Most co-reported drugs: Milbemycin Oxime + Spinosad (6 reports), Selamectin (4 reports), Spinosad (3 reports), Ivermectin (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.