Wobbliness

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VeDDRA Code: 2871

1,150 adverse event reports referencing this reaction

1,150
Total Reports
177
Deaths
1540.0%
Death Rate

Species Most Affected

Dog 810
Cat 326
Horse 7
Cattle 2
Pig 2
Pheasant 1
Unknown 1
Other Equids 1

Breeds Most Affected

Domestic Shorthair 215
Retriever - Labrador 110
Crossbred Canine/dog 54
Chihuahua 50
Retriever - Golden 36
Shepherd Dog - German 35
Shih Tzu 33
Terrier - Yorkshire 31
Domestic Longhair 25
Dog (unknown) 24

Associated Drugs

Bedinvetmab 248
Pyrantel Pamoate;Sarolaner 80
Fluralaner 13.64% 12-Week Chew 79
Gabapentin 74
Carprofen 60
Maropitant Citrate 53
Frunevetmab 50
Afoxolaner 47
Buprenorphine 43
Milbemycin Oxime + Praziquantel 33
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 32
Fluralaner/Moxidectin Spot-On 32
Lotilaner 30
Eprinomectin + Esafoxolaner + Praziquantel 29
Trilostane 28
Sarolaner 27
Grapiprant 27
Pimobendan 26
Cefovecin 26
Ivermectin + Pyrantel As Pamoate Salt 26

Data Summary

Metric Value
Total reports referencing reaction 1,150
Reports with fatal outcome 177
Case-fatality rate (reported events) 1540.0%
Species observed 8
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2871.

Wobbliness Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 1,150 adverse event reports that reference Wobbliness as a reaction term, including 177 reports with a death outcome — a 1540.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2871, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Wobbliness appears most frequently in reports for Dog (810 reports), Cat (326 reports), Horse (7 reports) — with Dog dominating at 810 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (215), Retriever - Labrador (110), Crossbred Canine/dog (54). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Wobbliness are Bedinvetmab (248 reports), Pyrantel Pamoate;Sarolaner (80 reports), Fluralaner 13.64% 12-Week Chew (79 reports), Gabapentin (74 reports), with Bedinvetmab appearing alongside this reaction in 248 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial