Reaction profile

The FDA adverse-event record for peritonitis

859 FDA reports name peritonitis, a high-volume reaction in the CVM extract (VeDDRA 253). Plate stamps and neighbourhood peers follow.

#439 of 2,481
by report volume (all reactions)
859
reports citing this reaction
58.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Peritonitis has 859 reports now versus 848 in that prior snapshot: 11 more (1.3%).

Report change
+11
Death-coded reports
+5
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Peritonitis changes

FDA AER · VeDDRA plate

Code 253 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 859 reports
  • DEATH-HOT 58.6%
  • UPPER-Q #439/2481
  • PHOTO-FINISH Muscle weakness NOS
  • SPECIES-DOG Dog · 734
  • DRUG-LEAD Deracoxib · 297
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Muscle weakness NOS (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Peritonitis

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Swelling around eye · near864Heavy breathing · near863Peritonitis · this reaction859Muscle weakness NOS · near858Conjunctivitis · near857Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Peritonitis

Peritonitis: high death-coded share in the FDA AER plate

Signature read: 503 death-coded reports is a heavy tail count for Peritonitis in the CVM extract. Report volume is upper-third scale: 859 named reports in the openFDA extract. Death-coded share is upper-third: 503 of 859 reports (58.6% of named reports). Nearest volume peer: Muscle weakness NOS (±1 reports). Lead species Dog (734). Lead co-reported drug Deracoxib (297).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 734
Cat 53
Cattle 51
Horse 11
Chicken 6
Pig 2
Other Canids 1
Donkey 1

Breeds Most Affected

Retriever - Labrador 220
Rottweiler 63
Crossbred Canine/dog 57
Retriever - Golden 37
Domestic Shorthair 29
Shepherd Dog - German 23
Mastiff 19
Cattle (unknown) 17
Boxer (German Boxer) 16
Dog (unknown) 16

Associated Drugs

Deracoxib 297
Carprofen 155
Firocoxib 101
Maropitant Citrate 87
Tramadol 86
Meloxicam 77
Isoflurane 49
Enrofloxacin 48
Gabapentin 47
Buprenorphine 38
Firocoxib 227 Mg Chewable 34
Propofol 27
Hydromorphone 23
Fentanyl 23
Metronidazole 22
Tylosin Phosphate 21
Famotidine 21
Cephalexin 20
Monensin Sodium 19
Ketamine 18

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Peritonitis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (859 here).

Similar death-coded share

Nearest other reactions by death-coded share (58.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Peritonitis (#439 of 2,481 by report volume); death-coded 58.6%. PlainBreed reaction plate · death-coded report count stamp 503 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →