Reaction profile

The FDA adverse-event record for peritonitis

837 FDA adverse-event reports reference peritonitis (VeDDRA 253). See the species, breeds, and drugs most associated with it below.

837
reports citing this reaction
58.8%
death-coded share
Dog
most-affected species
Deracoxib
most-associated drug
Verify with FDA CVM →
837
Total Reports
492
Deaths
58.8%
Death Rate

Species Most Affected

Dog 717
Cat 51
Cattle 48
Horse 11
Chicken 6
Pig 2
Other Canids 1
Donkey 1

Breeds Most Affected

Retriever - Labrador 218
Rottweiler 63
Crossbred Canine/dog 56
Retriever - Golden 35
Domestic Shorthair 28
Shepherd Dog - German 21
Mastiff 19
Cattle (unknown) 17
Boxer (German Boxer) 16
Siberian Husky 15

Associated Drugs

Deracoxib 295
Carprofen 152
Firocoxib 101
Tramadol 85
Maropitant Citrate 80
Meloxicam 73
Enrofloxacin 45
Isoflurane 43
Gabapentin 42
Buprenorphine 35
Firocoxib 227 Mg Chewable 34
Propofol 24
Hydromorphone 22
Fentanyl 22
Tylosin Phosphate 21
Cephalexin 20
Metronidazole 20
Famotidine 19
Monensin Sodium 18
Cefazolin 18

Peritonitis Reaction Insights

837 reports name Peritonitis; 492 recorded a death outcome (58.8% of reported events, not a population-level mortality rate). VeDDRA code: 253.

By species: Dog (717 reports), Cat (51 reports), Cattle (48 reports). By breed: Retriever - Labrador (218), Rottweiler (63), Crossbred Canine/dog (56).

Most co-reported drugs: Deracoxib (295 reports), Carprofen (152 reports), Firocoxib (101 reports), Tramadol (85 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.