Eosinopenia

Verify with FDA CVM →

VeDDRA Code: 2862

522 adverse event reports referencing this reaction

522
Total Reports
152
Deaths
2910.0%
Death Rate

Species Most Affected

Dog 376
Cat 146

Breeds Most Affected

Domestic Shorthair 90
Retriever - Labrador 53
Crossbred Canine/dog 27
Retriever - Golden 26
Dachshund (unspecified) 17
Shepherd Dog - German 16
Shepherd Dog - Australian 16
Beagle 13
Boxer (German Boxer) 13
Bulldog - French 11

Associated Drugs

Maropitant Citrate 91
Gabapentin 50
Buprenorphine 45
Carprofen 43
Oclacitinib Maleate 41
Prednisone 38
Bedinvetmab 37
Robenacoxib 34
Afoxolaner 31
Frunevetmab 30
Propofol 28
Ilunocitinib 27
Cefovecin 26
Doxycycline 26
Enrofloxacin 25
Famotidine 25
Diphenhydramine 24
Metronidazole 24
Meloxicam 24
Eprinomectin + Esafoxolaner + Praziquantel 24

Data Summary

Metric Value
Total reports referencing reaction 522
Reports with fatal outcome 152
Case-fatality rate (reported events) 2910.0%
Species observed 2
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2862.

Eosinopenia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 522 adverse event reports that reference Eosinopenia as a reaction term, including 152 reports with a death outcome — a 2910.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2862, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Eosinopenia appears most frequently in reports for Dog (376 reports), Cat (146 reports) — with Dog dominating at 376 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (90), Retriever - Labrador (53), Crossbred Canine/dog (27). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Eosinopenia are Maropitant Citrate (91 reports), Gabapentin (50 reports), Buprenorphine (45 reports), Carprofen (43 reports), with Maropitant Citrate appearing alongside this reaction in 91 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial