Reaction profile

The FDA adverse-event record for eosinopenia

991 FDA reports name eosinopenia, a high-volume reaction in the CVM extract (VeDDRA 2862). Plate stamps and neighbourhood peers follow.

#396 of 2,481
by report volume (all reactions)
991
reports citing this reaction
27.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Eosinopenia has 720 reports now versus 646 in that prior snapshot: 74 more (11.5%).

Report change
+74
Death-coded reports
+12
Death-coded share
−1.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Eosinopenia changes

FDA AER · VeDDRA plate

Code 2862 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 991 reports
  • DEATH-HOT 27.4%
  • UPPER-Q #396/2481
  • PHOTO-FINISH Lack of efficacy (tap…
  • SPECIES-DOG Dog · 528
  • DRUG-LEAD Maropitant Citrate · 153
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Lack of efficacy (tapeworm) (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Eosinopenia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal menace refle… · near993Skin inflammation NOS · near993Eosinopenia · this reaction991Lack of efficacy (tap… · near990Stopper, abnormal · near984Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Eosinopenia

Eosinopenia: high death-coded share in the FDA AER plate

Signature read: 272 death-coded reports is a heavy tail count for Eosinopenia in the CVM extract. Report volume is upper-third scale: 991 named reports in the openFDA extract. Death-coded share is upper-third: 272 of 991 reports (27.4% of named reports). Nearest volume peer: Lack of efficacy (tapeworm) (±1 reports). Lead species Dog (528). Lead co-reported drug Maropitant Citrate (153).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 528
Cat 191
Goat 1

Breeds Most Affected

Domestic Shorthair 120
Retriever - Labrador 79
Retriever - Golden 35
Crossbred Canine/dog 35
Shepherd Dog - German 27
Shepherd Dog - Australian 21
Dachshund (unspecified) 19
Beagle 19
Boxer (German Boxer) 17
Bulldog - French 16

Associated Drugs

Maropitant Citrate 153
Ilunocitinib 85
Oclacitinib Maleate 77
Gabapentin 75
Carprofen 62
Prednisone 60
Buprenorphine 55
Bedinvetmab 49
Robenacoxib 46
Metronidazole 41
Diphenhydramine 40
Doxycycline 38
Afoxolaner 38
Frunevetmab 38
Famotidine 37
Lotilaner 35
Cefovecin 33
Rabies Vaccine 33
Moxidectin 31
Enrofloxacin 30

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Eosinopenia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (27.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Eosinopenia (#396 of 2,481 by report volume); death-coded 27.4%. PlainBreed reaction plate · death-coded report count stamp 272 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →