Reaction profile

The FDA adverse-event record for blood loss nos

208 FDA adverse-event reports reference blood loss nos (VeDDRA 1352). See the species, breeds, and drugs most associated with it below.

208
reports citing this reaction
42.3%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
208
Total Reports
88
Deaths
42.3%
Death Rate

Species Most Affected

Dog 170
Cat 24
Human 7
Horse 3
Cattle 2
Unknown 2

Breeds Most Affected

Retriever - Labrador 16
Dog (unknown) 14
Crossbred Canine/dog 13
Domestic Shorthair 10
Beagle 9
Unknown 9
Shepherd Dog - German 8
Mixed (Dog) 5
Cat (unknown) 5
Chihuahua 5

Associated Drugs

Carprofen 20
Maropitant Citrate 20
Milbemycin Oxime + Spinosad 18
Bedinvetmab 16
Afoxolaner 12
Grapiprant 12
Oclacitinib Maleate 11
Gabapentin 10
Firocoxib 9
Moxidectin 9
Enrofloxacin 8
Cefazolin 8
Buprenorphine 8
Propofol 8
Spinosad 7
Fluralaner Chew Tablets 7
Butorphanol 7
Fluralaner 13.64% 12-Week Chew 7
Prednisone 7
Frunevetmab 7

Blood loss NOS Reaction Insights

208 reports name Blood loss NOS; 88 recorded a death outcome (42.3% of reported events, not a population-level mortality rate). VeDDRA code: 1352.

By species: Dog (170 reports), Cat (24 reports), Human (7 reports). By breed: Retriever - Labrador (16), Dog (unknown) (14), Crossbred Canine/dog (13).

Most co-reported drugs: Carprofen (20 reports), Maropitant Citrate (20 reports), Milbemycin Oxime + Spinosad (18 reports), Bedinvetmab (16 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.