Reaction profile

The FDA adverse-event record for nt - chronic interstitial nephritis

31 FDA reports name nt - chronic interstitial nephritis, a lower-volume reaction in the CVM extract (VeDDRA 2360). Plate stamps and neighbourhood peers follow.

#1977 of 2,481
by report volume (all reactions)
31
reports citing this reaction
100.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. NT - chronic interstitial nephritis has 31 reports now versus 31 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to NT - chronic interstitial nephritis changes

FDA AER · VeDDRA plate

Code 2360 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 31 reports
  • DEATH-HOT 100.0%
  • LOWER-Q #1977/2481
  • PHOTO-FINISH ABNORMAL TEST RESULT,…
  • SPECIES-DOG Dog · 26
  • DRUG-LEAD Spinosad · 5
  • DESK-WIDE 19 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around NT - chronic interstitial nephritis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ABNORMAL TEST RESULT,… · near31ALBUMIN HIGH, URINE · near31BILE ACIDS ABNORMAL,… · near31Clonic seizure · near31NT - chronic intersti… · thi…31Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around NT - chronic interstitial nephritis

NT - chronic interstitial nephritis: high death-coded share in the FDA AER plate

Signature read: NT - chronic interstitial nephritis's 100.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 31 named reports in the openFDA extract. Death-coded share is upper-third: 31 of 31 reports (100.0% of named reports). Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports). Lead species Dog (26). Lead co-reported drug Spinosad (5).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 26
Cat 5

Breeds Most Affected

Domestic Shorthair 5
Retriever - Labrador 4
Spitz - German Pomeranian 3
Dachshund (unspecified) 3
Shih Tzu 2
Terrier - Boston 1
Sheepdog - Shetland 1
Maltese 1
Saint Bernard Dog 1
Bulldog 1

Associated Drugs

Spinosad 5
Milbemycin Oxime + Spinosad 5
Carprofen 4
Afoxolaner 3
Meloxicam 3
Fluralaner Chew Tablets 3
Fipronil 2
Acepromazine 2
Cefazolin 2
Isoflurane 2
Robenacoxib 2
Phenobarbital 2
Gabapentin 2
Buprenorphine 2
Grapiprant 2
Lufenuron + Milbemycin Oxime 1
Polysulfated Glycosaminoglycan 1
Ivermectin + Pyrantel As Pamoate Salt 1
Rabies Virus, Kv 1
Hetastarch 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for NT - chronic interstitial nephritis (#1977 of 2,481 by report volume); death-coded 100.0%. PlainBreed reaction plate · death-coded share stamp 100.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →