Reaction profile

The FDA adverse-event record for chewing - pruritus (see also 'oral cavity disorders')

735 FDA reports name chewing - pruritus (see also 'oral cavity disorders'), a high-volume reaction in the CVM extract (VeDDRA 2618). Plate stamps and neighbourhood peers follow.

#487 of 2,481
by report volume (all reactions)
735
reports citing this reaction
1.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chewing - pruritus (see also 'Oral cavity disorders') has 478 reports now versus 478 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chewing - pruritus (see also 'Oral cavity disorders') changes

FDA AER · VeDDRA plate

Code 2618 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 735 reports
  • DEATH-LOW 1.8%
  • UPPER-Q #487/2481
  • PHOTO-FINISH Contamination, Partic…
  • SPECIES-DOG Dog · 402
  • DRUG-LEAD Afoxolaner · 56
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Contamination, Particulate Matter (±4 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Chewing - pruritus

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Dullness · near739Chewing - pruritus (s… · thi…735Contamination, Partic… · near731Application site pain · near729Generalised weakness · near729Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Chewing - pruritus (see also 'Oral cavity disorders')

Chewing - pruritus (see also 'Oral cavity disorders'): low death-coded share in the FDA AER plate

Signature read: Chewing - pruritus (see also 'Oral cavity disorders')'s 1.8% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 735 named reports in the openFDA extract. Death-coded share is lower-third: 13 of 735 reports (1.8% of named reports). Nearest volume peer: Contamination, Particulate Matter (±4 reports). Lead species Dog (402). Lead co-reported drug Afoxolaner (56).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Afoxolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 402
Cat 73
Guinea Pig 1
Ferret 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 44
Crossbred Canine/dog 33
Retriever - Labrador 27
Shepherd Dog - German 26
Chihuahua 25
Terrier - Yorkshire 19
Retriever - Golden 19
Dog (unknown) 14
Maltese 13
Shih Tzu 13

Associated Drugs

Afoxolaner 56
Fluralaner Chew Tablets 50
Pyrantel Pamoate;Sarolaner 48
Imidacloprid + Moxidectin 41
Nitenpyram 29
Fluralaner 13.64% 12-Week Chew 29
Ivermectin + Pyrantel As Pamoate Salt 23
Flumethrin-Imidacloprid 20
Moxidectin 20
Selamectin 19
Sarolaner 19
Fluralaner Spot-On Solution 17
Shampoo 17
Carprofen 14
Trilostane 13
Oclacitinib Maleate 13
Milbemycin Oxime + Spinosad 12
Prednisone 11
Lotilaner 11
Imidacloprid 10

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Chewing - pruritus (see also 'Oral cavity disorders'), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (735 here).

Similar death-coded share

Nearest other reactions by death-coded share (1.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chewing - pruritus (see also 'Oral cavity disorders') (#487 of 2,481 by report volume); death-coded 1.8%. PlainBreed reaction plate · death-coded share stamp 1.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →