Reaction profile

The FDA adverse-event record for acne

65 FDA adverse-event reports reference acne (VeDDRA 905). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1608 of 2,481
by report volume (all reactions)
65
reports citing this reaction
1.5%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Acne has 65 reports now versus 65 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Acne changes

FDA AER · VeDDRA plate

Code 905 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 65 reports
  • DEATH-LOW 1.5%
  • MID-PACK #1608/2481
  • PHOTO-FINISH Gut sounds decreased
  • SPECIES-CAT Cat · 38
  • DRUG-LEAD Milbemycin Oxime… · 13
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Gut sounds decreased (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Acne

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Acne · this reaction65Gut sounds decreased · near65Hair standing on end · near65Immune-mediated polya… · near65Inversion of albumin/… · near65Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Acne

Acne: low death-coded share in the FDA AER plate

Signature read: 1 death-coded reports is a thin tail count for Acne in the CVM extract. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 1 of 65 reports (1.5% of named reports). Nearest volume peer: Gut sounds decreased (±0 reports). Lead species Cat (38). Lead co-reported drug Milbemycin Oxime + Spinosad (13).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 38
Dog 24
Human 3

Breeds Most Affected

Domestic Shorthair 23
Domestic Longhair 6
Retriever - Labrador 3
Unknown 3
Maine Coon 3
Bulldog 2
Cat (unknown) 2
Boxer (German Boxer) 2
Deutsche Dogge, Great Dane 2
Terrier - Boston 2

Associated Drugs

Milbemycin Oxime + Spinosad 13
Frunevetmab 12
Cefovecin 7
Bexagliflozin 5
Imidacloprid + Moxidectin 4
Enrofloxacin 3
Afoxolaner 3
Milbemycin Oxime + Praziquantel 3
Oclacitinib Maleate 3
Anti-Il31 Mab Mcs Lot #1283563 3
Selmectin 2
Nitenpyram 2
Fipronil 2
Milbemycin Oxime 2
Antibiotic (Unknown) 2
Fluralaner Spot-On Solution 2
Polysulfated Glycosaminoglycan 2
Thiamazole 2
Pyrantel Pamoate;Sarolaner 2
Mirtazapine 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Acne, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (1.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Acne (#1608 of 2,481 by report volume); death-coded 1.5%. PlainBreed reaction plate · death-coded report count stamp 1 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →