Hypovolaemic shock

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VeDDRA Code: 2675

47 adverse event reports referencing this reaction

47
Total Reports
25
Deaths
5320.0%
Death Rate

Species Most Affected

Dog 40
Cat 7

Breeds Most Affected

Retriever - Labrador 11
Terrier - Bull - American Pit 4
Domestic Shorthair 4
Shepherd Dog - German 4
Pit Bull 2
Shih Tzu 1
Norwegian Forest 1
Shepherd Dog - Australian 1
Retriever - Golden 1
Terrier - Jack Russell 1

Associated Drugs

Gabapentin 9
Bedinvetmab 9
Carprofen 6
Buprenorphine 5
Moxidectin 5
Maropitant Citrate 5
Polysulfated Glycosaminoglycan 5
Butorphanol 4
Oclacitinib Maleate 4
Rabies Vaccine 4
Melarsomine Dihydrochloride 4
Afoxolaner 4
Galliprant 4
Pantoprazole 3
Prednisone 3
Deracoxib 3
Diphenhydramine 3
Oxygen 3
Enrofloxacin 3
Isoflurane 3

Data Summary

Metric Value
Total reports referencing reaction 47
Reports with fatal outcome 25
Case-fatality rate (reported events) 5320.0%
Species observed 2
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2675.

Hypovolaemic shock Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 47 adverse event reports that reference Hypovolaemic shock as a reaction term, including 25 reports with a death outcome — a 5320.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2675, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Hypovolaemic shock appears most frequently in reports for Dog (40 reports), Cat (7 reports) — with Dog dominating at 40 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (11), Terrier - Bull - American Pit (4), Domestic Shorthair (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Hypovolaemic shock are Gabapentin (9 reports), Bedinvetmab (9 reports), Carprofen (6 reports), Buprenorphine (5 reports), with Gabapentin appearing alongside this reaction in 9 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial