Reaction profile

The FDA adverse-event record for scratching

7,139 FDA reports name scratching, a high-volume reaction in the CVM extract (VeDDRA 959). Plate stamps and neighbourhood peers follow.

#70 of 2,481
by report volume (all reactions)
7,139
reports citing this reaction
1.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Scratching has 7,139 reports now versus 7,064 in that prior snapshot: 75 more (1.1%).

Report change
+75
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Scratching changes

FDA AER · VeDDRA plate

Code 959 VOL-HIGH

VOL-HIGH · DEATH-LOW · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-HIGH 7,139 reports
  • DEATH-LOW 1.1%
  • TOP-DECILE #70/2481
  • PHOTO-FINISH Lack of efficacy (end…
  • SPECIES-DOG Dog · 5,066
  • DRUG-LEAD Nitenpyram · 1,173
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Lack of efficacy (endoparasite) - whipworm (±13 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Scratching

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Containers, Leaking · near7289Trembling · near7230Scratching · this reaction7139Lack of efficacy (end… · near7126Underfilling, Package · near6969Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Scratching

Scratching: low death-coded share in the FDA AER plate

Signature read: 7,139 reports place Scratching in the upper third of FDA AER volume (#70 of 2,481). Report volume is upper-third scale: 7,139 named reports in the openFDA extract. Death-coded share is lower-third: 75 of 7,139 reports (1.1% of named reports). Nearest volume peer: Lack of efficacy (endoparasite) - whipworm (±13 reports). Lead species Dog (5,066). Lead co-reported drug Nitenpyram (1,173).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Nitenpyram appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 5,066
Cat 1,856
Cattle 208
Unknown 2
Horse 2
Human 2
Goat 1
Donkey 1
Rabbit 1

Breeds Most Affected

Domestic Shorthair 1,005
Crossbred Canine/dog 382
Retriever - Labrador 377
Dog (unknown) 328
Chihuahua 324
Shih Tzu 250
Terrier - Yorkshire 241
Shepherd Dog - German 232
Domestic Longhair 220
Retriever - Golden 170

Associated Drugs

Nitenpyram 1,173
Afoxolaner 921
Milbemycin Oxime + Spinosad 876
Spinosad 627
Fluralaner Chew Tablets 422
Ivermectin + Pyrantel As Pamoate Salt 249
Selamectin 235
Frunevetmab 234
Lotilaner 196
Fluralaner Spot-On Solution 188
Fluralaner 13.64% 12-Week Chew 171
Pyrantel Pamoate;Sarolaner 140
Imidacloprid + Moxidectin 137
Selamectin;Sarolaner 122
Moxidectin 97
Oclacitinib Maleate 91
Milbemycin Oxime + Praziquantel 90
Ivermectin 0.5% Pour-On Topical Solution 85
Sarolaner 79
Portech App Gun 65 Ml Ivomec/Eprinex 78

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Scratching, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (1.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Scratching (#70 of 2,481 by report volume); death-coded 1.1%. PlainBreed reaction plate · report volume stamp 7,139 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →