Recovery prolonged

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VeDDRA Code: 1904

570 adverse event reports referencing this reaction

570
Total Reports
91
Deaths
1600.0%
Death Rate

Species Most Affected

Dog 278
Cat 254
Horse 18
Pig 4
Mouse 3
Rabbit 2
Guinea Pig 2
Rat 1
Cattle 1
Other Mustelids 1

Breeds Most Affected

Domestic Shorthair 92
Dog (unknown) 65
Domestic (unspecified) 44
Cat (unknown) 34
Retriever - Labrador 30
Unknown 27
Domestic Longhair 21
Crossbred Canine/dog 15
Shih Tzu 13
Cat (other) 13

Associated Drugs

Isoflurane 144
Dexmedetomidine Hydrochloride 117
Propofol 89
Ketamine Hydrochloride 84
Butorphanol 80
Buprenorphine 72
Butorphanol Tartrate 61
Atipamezole Hydrochloride 53
Ketamine 50
Alfaxalone 38
Dexmedetomidine 37
Tiletamine Hcl; Zolazapam Hcl 31
Midazolam 30
Carprofen 29
Acepromazine Maleate 27
Meloxicam 26
Robenacoxib 23
Cefovecin 23
Atropine 21
Atipamezole 20

Data Summary

Metric Value
Total reports referencing reaction 570
Reports with fatal outcome 91
Case-fatality rate (reported events) 1600.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1904.

Recovery prolonged Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 570 adverse event reports that reference Recovery prolonged as a reaction term, including 91 reports with a death outcome — a 1600.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1904, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Recovery prolonged appears most frequently in reports for Dog (278 reports), Cat (254 reports), Horse (18 reports) — with Dog dominating at 278 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (92), Dog (unknown) (65), Domestic (unspecified) (44). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Recovery prolonged are Isoflurane (144 reports), Dexmedetomidine Hydrochloride (117 reports), Propofol (89 reports), Ketamine Hydrochloride (84 reports), with Isoflurane appearing alongside this reaction in 144 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial