Reaction profile

The FDA adverse-event record for pr-nerve(s), lesion(s)

Name: PR-NERVE(S), LESION(S) - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

13 FDA reports name pr-nerve(s), lesion(s), a lower-volume reaction in the CVM extract (VeDDRA 99655). Plate stamps and neighbourhood peers follow.

#2369 of 2,481
by report volume (all reactions): 13
reports citing this reaction: 100.0%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-NERVE(S), LESION(S) has 13 reports now versus 13 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-NERVE(S), LESION(S) changes

FDA AER · VeDDRA plate

Code 99655 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 13 reports
DEATH-HOT 100.0%
BOTTOM-DECILE #2369/2481
PHOTO-FINISH Abnormal digital pulse
SPECIES-DOG Dog · 6
DRUG-LEAD Milbemycin Oxime… · 3
DESK-WIDE 9 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal digital pulse (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around PR-NERVE, LESION

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around PR-NERVE(S), LESION(S)

PR-NERVE(S), LESION(S): high death-coded share in the FDA AER plate

Signature read: PR-NERVE(S), LESION(S)'s 100.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 13 named reports in the openFDA extract. Death-coded share is upper-third: 13 of 13 reports (100.0% of named reports). Nearest volume peer: Abnormal digital pulse (±0 reports). Lead species Dog (6). Lead co-reported drug Milbemycin Oxime + Spinosad (3).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 6

Cat 4

Cattle 3

Breeds Most Affected

Retriever - Labrador 3

Domestic (unspecified) 2

Domestic Shorthair 2

Holstein-Friesian also known as Holstein 1

Cattle (unknown) 1

Boxer (German Boxer) 1

Terrier - Boston 1

Retriever - Golden 1

Crossbred Bovine/Cattle 1

Associated Drugs

Milbemycin Oxime + Spinosad 3

Ceftiofur 2

Amoxicillin, Clavulanate 1

Glycosaminoglycan Polysulfate 1

Isoflurane Gas 1

Intravenous Fluids, Not Specified 1

Glucosamine, Msm, Creatine, Antioxidants 1

Carporfen 1

Acepromazine 1

Glycopyrrolate 1

Propofol 1

Morphine 1

Orbifloxacin 1

Spinosad 1

Polysulfated Glycosaminoglycan 1

Fluralaner Chew Tablets 1

Pyrantel Pamoate 1

Carprofen 1

Grapiprant 1

Bexagliflozin 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-NERVE(S), LESION(S) (#2369 of 2,481 by report volume); death-coded 100.0%. PlainBreed reaction plate · death-coded share stamp 100.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →