Reaction profile

The FDA adverse-event record for nasal cavity and sinus disorder nos

106 FDA adverse-event reports reference nasal cavity and sinus disorder nos (VeDDRA 865). See the species, breeds, and drugs most associated with it below.

106
reports citing this reaction
14.2%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
106
Total Reports
15
Deaths
14.2%
Death Rate

Species Most Affected

Dog 65
Cat 29
Human 8
Horse 3
Cattle 1

Breeds Most Affected

Domestic Shorthair 21
Unknown 8
Crossbred Canine/dog 8
Retriever - Labrador 6
Domestic (unspecified) 5
Chihuahua 3
Shepherd Dog - German 3
Beagle 2
Spaniel - Cocker American 2
Retriever - Golden 2

Associated Drugs

Carprofen 9
Milbemycin Oxime + Spinosad 9
Maropitant Citrate 9
Selamectin 8
Imidacloprid + Moxidectin 8
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 7
Cefovecin Sodium 6
Enrofloxacin 6
Spinosad 5
Cefovecin 5
Nitenpyram 4
Trilostane 4
Fenbendazole 4
Cyclosporine A 4
Doxycycline 4
Meloxicam 3
Milbemycin, Lufenuron 3
Amoxicillin/Clavulanic Acid 3
Butorphanol 3
Praziquantel 3

Nasal cavity and sinus disorder NOS Reaction Insights

106 reports name Nasal cavity and sinus disorder NOS; 15 recorded a death outcome (14.2% of reported events, not a population-level mortality rate). VeDDRA code: 865.

By species: Dog (65 reports), Cat (29 reports), Human (8 reports). By breed: Domestic Shorthair (21), Unknown (8), Crossbred Canine/dog (8).

Most co-reported drugs: Carprofen (9 reports), Milbemycin Oxime + Spinosad (9 reports), Maropitant Citrate (9 reports), Selamectin (8 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.