Reaction profile

The FDA adverse-event record for unable to jump

644 FDA adverse-event reports reference unable to jump (VeDDRA 2394). See the species, breeds, and drugs most associated with it below.

644
reports citing this reaction
11.2%
death-coded share
Dog
most-affected species
Pyrantel Pamoate;Sarolaner
most-associated drug
Verify with FDA CVM →
644
Total Reports
72
Deaths
11.2%
Death Rate

Species Most Affected

Dog 451
Cat 192
Chinchilla 1

Breeds Most Affected

Domestic Shorthair 115
Crossbred Canine/dog 52
Chihuahua 29
Retriever - Labrador 26
Shih Tzu 19
Beagle 17
Terrier (unspecified) 15
Domestic Longhair 14
Domestic Mediumhair 13
Terrier - Jack Russell 12

Associated Drugs

Pyrantel Pamoate;Sarolaner 51
Fluralaner 13.64% 12-Week Chew 43
Sarolaner 41
Fluralaner Chew Tablets 39
Frunevetmab 39
Oclacitinib Maleate 37
Bedinvetmab 36
Trilostane 34
Afoxolaner 32
Ivermectin + Pyrantel As Pamoate Salt 31
Maropitant Citrate 29
Gabapentin 26
Carprofen 24
Fluralaner Spot-On Solution 22
Lotilaner 22
Selamectin;Sarolaner 20
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 20
Cefovecin 18
Selamectin 18
Prednisone 17

Unable to jump Reaction Insights

644 reports name Unable to jump; 72 recorded a death outcome (11.2% of reported events, not a population-level mortality rate). VeDDRA code: 2394.

By species: Dog (451 reports), Cat (192 reports), Chinchilla (1 reports). By breed: Domestic Shorthair (115), Crossbred Canine/dog (52), Chihuahua (29).

Most co-reported drugs: Pyrantel Pamoate;Sarolaner (51 reports), Fluralaner 13.64% 12-Week Chew (43 reports), Sarolaner (41 reports), Fluralaner Chew Tablets (39 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.