Reaction profile

The FDA adverse-event record for lack of efficacy (endoparasite) - trichostrongylus

37 FDA reports name lack of efficacy (endoparasite) - trichostrongylus, a lower-volume reaction in the CVM extract (VeDDRA 2794). Plate stamps and neighbourhood peers follow.

#1896 of 2,481
by report volume (all reactions)
37
reports citing this reaction
16.2%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (endoparasite) - Trichostrongylus has 37 reports now versus 37 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (endoparasite) - Trichostrongylus changes

FDA AER · VeDDRA plate

Code 2794 VOL-TRACE

VOL-TRACE · DEATH-ELEV · LOWER-Q · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 37 reports
  • DEATH-ELEV 16.2%
  • LOWER-Q #1896/2481
  • PHOTO-FINISH Blistering of mouth
  • SPECIES-CATTLE Cattle · 32
  • DRUG-LEAD Eprinomectin · 24
  • DESK-WIDE 15 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Blistering of mouth (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Lack of efficacy - Trichostrongylus

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Blistering of mouth · near37CARBON DIOXIDE HIGH,… · near37Cartilage degeneration · near37Cleft palate · near37Lack of efficacy (end… · thi…37Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lack of efficacy (endoparasite) - Trichostrongylus

What the FDA AER plate says about Lack of efficacy (endoparasite) - Trichostrongylus

Signature read: 37 reports place Lack of efficacy (endoparasite) - Trichostrongylus in the lower third of FDA AER volume (#1896 of 2,481). Report volume is lower-third scale: 37 named reports in the openFDA extract. 6 of 37 reports were death-coded (16.2% of named reports, not a population mortality rate). Nearest volume peer: Blistering of mouth (±0 reports). Lead species Cattle (32). Lead co-reported drug Eprinomectin (24).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Eprinomectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 32
Dog 3
Sheep 2

Breeds Most Affected

Cattle (other) 9
Aberdeen Angus 8
Cattle (unknown) 5
Crossbred Bovine/Cattle 3
Retriever - Labrador 2
Brahman 1
Beefmaster 1
Collie - Rough-haired 1
Holstein-Friesian also known as Holstein 1
Brangus 1

Associated Drugs

Eprinomectin 24
Oxfendazole 5
Moxidectin 4
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid 4
Doramectin 4
Fenbendazole 3
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea, Modified Live Virus + Campylobacter Fetus Bacterin + Leptospira Canicola Bacterin + Leptospira Grippotyphosa Bacterin + Leptospira Hardjo Bacterin + Leptospira Icterohaemorrhagiae Bacterin + Leptospira Pomona Bacterin 2
Clorsulon + Ivermectin 2
Ibr, Bvd Cp Type1, Ncp Type 1 And 2, Pi3, Brsv, Killed Virus 1
7-Way Vaccine For Blackleg, Enterotoxemia And Clostridial Pathogens 1
Bovine Rhinotracheitis/Viral Diarrhea/Parainfluenza 3/ Respiratory Syncytial Virus/ Mannheimia Haemolytica Toxoid Vaccine 1
Histophilus Somni Vaccine 1
Bacterin 1
Clostridium Chauvoei + Clostridium Novyi + Clostridium Perfringens Type C + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum + Clostridium Sordellii 1
Clostridium Chauvoei Bacterin Toxoid + Clostridium Novyi Bacterin Toxoid + Clostridium Perfringens Type C Bacterin Toxoid + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum Bacterin Toxoid + Clostridium Sordellii Bacterin Toxoid + Moraxella Bovis Bacterin Toxoid 1
Pyrantel Pamoate;Sarolaner 1
Unknown Pinkeye Vaccine 1
Monepantel 1
Ivermectin 1
Albendazole 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (endoparasite) - Trichostrongylus (#1896 of 2,481 by report volume); death-coded 16.2%. PlainBreed reaction plate · report volume stamp 37 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →