Lack of efficacy (endoparasite) - Trichostrongylus

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VeDDRA Code: 2794

35 adverse event reports referencing this reaction

35
Total Reports
6
Deaths
1710.0%
Death Rate

Species Most Affected

Cattle 30
Dog 3
Sheep 2

Breeds Most Affected

Cattle (other) 9
Aberdeen Angus 8
Cattle (unknown) 4
Crossbred Bovine/Cattle 3
Retriever - Labrador 2
Brahman 1
Collie - Rough-haired 1
Beefmaster 1
Holstein-Friesian also known as Holstein 1
Brangus 1

Associated Drugs

Eprinomectin 24
Oxfendazole 5
Moxidectin 4
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid 4
Fenbendazole 3
Doramectin 3
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea, Modified Live Virus + Campylobacter Fetus Bacterin + Leptospira Canicola Bacterin + Leptospira Grippotyphosa Bacterin + Leptospira Hardjo Bacterin + Leptospira Icterohaemorrhagiae Bacterin + Leptospira Pomona Bacterin 2
Ibr, Bvd Cp Type1, Ncp Type 1 And 2, Pi3, Brsv, Killed Virus 1
7-Way Vaccine For Blackleg, Enterotoxemia And Clostridial Pathogens 1
Bovine Rhinotracheitis/Viral Diarrhea/Parainfluenza 3/ Respiratory Syncytial Virus/ Mannheimia Haemolytica Toxoid Vaccine 1
Histophilus Somni Vaccine 1
Bacterin 1
Clostridium Chauvoei + Clostridium Novyi + Clostridium Perfringens Type C + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum + Clostridium Sordellii 1
Pyrantel Pamoate;Sarolaner 1
Clostridium Chauvoei Bacterin Toxoid + Clostridium Novyi Bacterin Toxoid + Clostridium Perfringens Type C Bacterin Toxoid + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum Bacterin Toxoid + Clostridium Sordellii Bacterin Toxoid + Moraxella Bovis Bacterin Toxoid 1
Unknown Pinkeye Vaccine 1
Monepantel 1
Ivermectin 1
Albendazole 1
Clorsulon + Ivermectin 1

Data Summary

Metric Value
Total reports referencing reaction 35
Reports with fatal outcome 6
Case-fatality rate (reported events) 1710.0%
Species observed 3
Breeds observed 14
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2794.

Lack of efficacy (endoparasite) - Trichostrongylus Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 35 adverse event reports that reference Lack of efficacy (endoparasite) - Trichostrongylus as a reaction term, including 6 reports with a death outcome — a 1710.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2794, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Lack of efficacy (endoparasite) - Trichostrongylus appears most frequently in reports for Cattle (30 reports), Dog (3 reports), Sheep (2 reports) — with Cattle dominating at 30 entries. Within those species, the breeds most often named alongside this reaction are Cattle (other) (9), Aberdeen Angus (8), Cattle (unknown) (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Lack of efficacy (endoparasite) - Trichostrongylus are Eprinomectin (24 reports), Oxfendazole (5 reports), Moxidectin (4 reports), Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid (4 reports), with Eprinomectin appearing alongside this reaction in 24 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial