Reaction profile

The FDA adverse-event record for lack of efficacy (endoparasite) - trichostrongylus

35 FDA adverse-event reports reference lack of efficacy (endoparasite) - trichostrongylus (VeDDRA 2794). See the species, breeds, and drugs most associated with it below.

35
reports citing this reaction
17.1%
death-coded share
Cattle
most-affected species
Eprinomectin
most-associated drug
Verify with FDA CVM →
35
Total Reports
6
Deaths
17.1%
Death Rate

Species Most Affected

Cattle 30
Dog 3
Sheep 2

Breeds Most Affected

Cattle (other) 9
Aberdeen Angus 8
Cattle (unknown) 4
Crossbred Bovine/Cattle 3
Retriever - Labrador 2
Brahman 1
Collie - Rough-haired 1
Beefmaster 1
Holstein-Friesian also known as Holstein 1
Brangus 1

Associated Drugs

Eprinomectin 24
Oxfendazole 5
Moxidectin 4
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid 4
Fenbendazole 3
Doramectin 3
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea, Modified Live Virus + Campylobacter Fetus Bacterin + Leptospira Canicola Bacterin + Leptospira Grippotyphosa Bacterin + Leptospira Hardjo Bacterin + Leptospira Icterohaemorrhagiae Bacterin + Leptospira Pomona Bacterin 2
Ibr, Bvd Cp Type1, Ncp Type 1 And 2, Pi3, Brsv, Killed Virus 1
7-Way Vaccine For Blackleg, Enterotoxemia And Clostridial Pathogens 1
Bovine Rhinotracheitis/Viral Diarrhea/Parainfluenza 3/ Respiratory Syncytial Virus/ Mannheimia Haemolytica Toxoid Vaccine 1
Histophilus Somni Vaccine 1
Bacterin 1
Clostridium Chauvoei + Clostridium Novyi + Clostridium Perfringens Type C + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum + Clostridium Sordellii 1
Pyrantel Pamoate;Sarolaner 1
Clostridium Chauvoei Bacterin Toxoid + Clostridium Novyi Bacterin Toxoid + Clostridium Perfringens Type C Bacterin Toxoid + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum Bacterin Toxoid + Clostridium Sordellii Bacterin Toxoid + Moraxella Bovis Bacterin Toxoid 1
Unknown Pinkeye Vaccine 1
Monepantel 1
Ivermectin 1
Albendazole 1
Clorsulon + Ivermectin 1

Lack of efficacy (endoparasite) - Trichostrongylus Reaction Insights

35 reports name Lack of efficacy (endoparasite) - Trichostrongylus; 6 recorded a death outcome (17.1% of reported events, not a population-level mortality rate). VeDDRA code: 2794.

By species: Cattle (30 reports), Dog (3 reports), Sheep (2 reports). By breed: Cattle (other) (9), Aberdeen Angus (8), Cattle (unknown) (4).

Most co-reported drugs: Eprinomectin (24 reports), Oxfendazole (5 reports), Moxidectin (4 reports), Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.