Reaction profile

The FDA adverse-event record for pr-pericardial effusion

13 FDA adverse-event reports reference pr-pericardial effusion (VeDDRA 99661). See the species, breeds, and drugs most associated with it below.

13
reports citing this reaction
100.0%
death-coded share
Cat
most-affected species
Dexmedetomidine Hydrochloride
most-associated drug
Verify with FDA CVM →
13
Total Reports
13
Deaths
100.0%
Death Rate

Species Most Affected

Cat 8
Dog 2
Horse 2
Cattle 1

Breeds Most Affected

Domestic (unspecified) 6
Domestic Shorthair 2
Holstein-Friesian also known as Holstein 1
Crossbred Canine/dog 1
Warmblood (unspecified) 1
Terrier - Bull - American Pit 1
Quarter Horse 1

Associated Drugs

Dexmedetomidine Hydrochloride 3
Cefovecin Sodium 2
Enrofloxacin 2
Ceftiofur 1
Deracoxib 1
Milbemycin 1
Ketamine Hydrochloride 1
Ceftiofur Crystalline Free Acid 1
Moxidectin 1
Rabies Virus, Kv 1
Triamcinolone 1
Diazepam 1
Anesthetic 1
Nacl, Sodium Lactate, Kcl & Calcium Chloride Dihydrate 1
Tiletamine Hcl; Zolazapam Hcl 1
Butorphanol 1
Cefovecin 1
Methylprednisolone Acetate 1
Insulin 1
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 1

PR-PERICARDIAL EFFUSION Reaction Insights

13 reports name PR-PERICARDIAL EFFUSION; 13 recorded a death outcome (100.0% of reported events, not a population-level mortality rate). VeDDRA code: 99661.

By species: Cat (8 reports), Dog (2 reports), Horse (2 reports). By breed: Domestic (unspecified) (6), Domestic Shorthair (2), Holstein-Friesian also known as Holstein (1).

Most co-reported drugs: Dexmedetomidine Hydrochloride (3 reports), Cefovecin Sodium (2 reports), Enrofloxacin (2 reports), Ceftiofur (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.