Reaction profile

The FDA adverse-event record for expired drug administered

695 FDA reports name expired drug administered, a high-volume reaction in the CVM extract (VeDDRA 99830). Plate stamps and neighbourhood peers follow.

#515 of 2,481
by report volume (all reactions)
695
reports citing this reaction
4.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Expired drug administered has 695 reports now versus 681 in that prior snapshot: 14 more (2.1%).

Report change
+14
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Expired drug administered changes

FDA AER · VeDDRA plate

Code 99830 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 695 reports
  • DEATH-LOW 4.9%
  • UPPER-Q #515/2481
  • PHOTO-FINISH Pleural effusion
  • SPECIES-DOG Dog · 493
  • DRUG-LEAD Spinosad · 69
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Pleural effusion (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Expired drug administered

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Expired drug administ… · thi…695Pleural effusion · near695Skin slough · near695Unwell · near694Dysphoria · near693Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Expired drug administered

Expired drug administered: low death-coded share in the FDA AER plate

Signature read: 695 reports place Expired drug administered in the upper third of FDA AER volume (#515 of 2,481). Report volume is upper-third scale: 695 named reports in the openFDA extract. Death-coded share is lower-third: 34 of 695 reports (4.9% of named reports). Nearest volume peer: Pleural effusion (±0 reports). Lead species Dog (493). Lead co-reported drug Spinosad (69).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 493
Cat 142
Unknown 21
Cattle 15
Horse 8
Pig 4
Human 4
Goat 2
Deer 2
Sheep 1

Breeds Most Affected

Domestic Shorthair 79
Dog (unknown) 58
Retriever - Labrador 44
Crossbred Canine/dog 33
Chihuahua 31
Terrier - Yorkshire 29
Unknown 28
Pit Bull 23
Shih Tzu 20
Cat (unknown) 19

Associated Drugs

Spinosad 69
Milbemycin Oxime + Spinosad 64
Nitenpyram 61
Afoxolaner 49
Imidacloprid + Moxidectin 41
Selamectin 33
Ivermectin + Pyrantel As Pamoate Salt 29
Fluralaner Spot-On Solution 26
Fluralaner 13.64% 12-Week Chew 19
Insulin Injectable Vial 18
Milbemycin Oxime + Praziquantel 15
Fluralaner Chew Tablets 14
Sarolaner 14
Moxidectin 13
Ivermectin + Pyrantel 11
Milbemycin Oxime 10
Phenylpropanolamine Hcl 9
Prednisone 8
Orbiflox/Momet/Posaco Eardrops 7
Fenbendazol Granules 7

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Expired drug administered, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (695 here).

Similar death-coded share

Nearest other reactions by death-coded share (4.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Expired drug administered (#515 of 2,481 by report volume); death-coded 4.9%. PlainBreed reaction plate · report volume stamp 695 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →