Reaction profile

The FDA adverse-event record for tongue inflammation

45 FDA adverse-event reports reference tongue inflammation (VeDDRA 288). See the species, breeds, and drugs most associated with it below.

45
reports citing this reaction
13.3%
death-coded share
Horse
most-affected species
Ivermectin + Praziquantel
most-associated drug
Verify with FDA CVM →
45
Total Reports
6
Deaths
13.3%
Death Rate

Species Most Affected

Horse 20
Dog 14
Cat 11

Breeds Most Affected

Domestic Shorthair 9
Horse (unknown) 6
Quarter Horse 4
Thoroughbred 3
Terrier - Boston 2
Crossbred Canine/dog 2
Domestic Mediumhair 2
Retriever - Golden 2
Paint 2
Horse (other) 2

Associated Drugs

Ivermectin + Praziquantel 13
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 4
Buprenorphine 4
Maropitant Citrate 4
Trilostane 3
Tigilanol Tiglate 3
Ivermectin/Praziquantel Paste 2
Melarsomine Dihydrochloride Injection 2
Spinosad 2
Dexmedetomidine Hydrochloride 2
Atipamezole Hydrochloride 2
Propofol 2
Sevoflurane 2
Chlorhexidine 2
Robenacoxib 2
Isoflurane 2
Oclacitinib Maleate 2
Dexamethasone 2
Butorphanol Tartrate 2
Imidacloprid + Moxidectin 1

Tongue inflammation Reaction Insights

45 reports name Tongue inflammation; 6 recorded a death outcome (13.3% of reported events, not a population-level mortality rate). VeDDRA code: 288.

By species: Horse (20 reports), Dog (14 reports), Cat (11 reports). By breed: Domestic Shorthair (9), Horse (unknown) (6), Quarter Horse (4).

Most co-reported drugs: Ivermectin + Praziquantel (13 reports), Ivermectin(1.55%)/Praziquantel(7.75%) Paste (4 reports), Buprenorphine (4 reports), Maropitant Citrate (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.