Reaction profile

The FDA adverse-event record for lung oedema

373 FDA reports name lung oedema, a high-volume reaction in the CVM extract (VeDDRA 849). Plate stamps and neighbourhood peers follow.

#770 of 2,481
by report volume (all reactions)
373
reports citing this reaction
62.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lung oedema has 373 reports now versus 370 in that prior snapshot: 3 more (0.8%).

Report change
+3
Death-coded reports
+1
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lung oedema changes

FDA AER · VeDDRA plate

Code 849 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 373 reports
  • DEATH-HOT 62.2%
  • MID-PACK #770/2481
  • PHOTO-FINISH Platelet disorder NOS
  • SPECIES-DOG Dog · 191
  • DRUG-LEAD Cefovecin Sodium · 27
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Platelet disorder NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Lung oedema

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Monocytopenia · near374Lung oedema · this reaction373Platelet disorder NOS · near373Wrong technique in dr… · near373Headache · near372Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lung oedema

Lung oedema: high death-coded share in the FDA AER plate

Signature read: Lung oedema's 62.2% death-coded share is among the highest in the openFDA reaction corpus. Report volume is upper-third scale: 373 named reports in the openFDA extract. Death-coded share is upper-third: 232 of 373 reports (62.2% of named reports). Nearest volume peer: Platelet disorder NOS (±0 reports). Lead species Dog (191). Lead co-reported drug Cefovecin Sodium (27).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 191
Cat 111
Cattle 54
Horse 8
Pig 4
Human 2
Sheep 1
Goat 1
Monkey 1

Breeds Most Affected

Domestic (unspecified) 61
Domestic Shorthair 19
Crossbred Canine/dog 19
Cattle (other) 15
Retriever - Labrador 14
Holstein-Friesian also known as Holstein 12
Chihuahua 12
Dog (unknown) 11
Cattle (unknown) 9
Cat (unknown) 9

Associated Drugs

Cefovecin Sodium 27
Milbemycin Oxime + Spinosad 25
Dexmedetomidine Hydrochloride 19
Spinosad 17
Pimobendan 16
Methylprednisolone Acetate 15
Moxidectin 15
Propofol 12
Tulathromycin 12
Melarsomine Dihydrochloride 11
Florfenicol 11
Monensin Sodium 10
Sevoflurane 9
Dexamethasone 9
Isoflurane 8
Cefovecin 8
Meloxicam 8
Furosemide 8
Ceftiofur 8
Carprofen 7

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lung oedema, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (373 here).

Similar death-coded share

Nearest other reactions by death-coded share (62.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lung oedema (#770 of 2,481 by report volume); death-coded 62.2%. PlainBreed reaction plate · death-coded share stamp 62.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →