Reaction profile

The FDA adverse-event record for lung oedema

367 FDA adverse-event reports reference lung oedema (VeDDRA 849). See the species, breeds, and drugs most associated with it below.

367
reports citing this reaction
62.1%
death-coded share
Dog
most-affected species
Cefovecin Sodium
most-associated drug
Verify with FDA CVM →
367
Total Reports
228
Deaths
62.1%
Death Rate

Species Most Affected

Dog 191
Cat 110
Cattle 51
Horse 6
Pig 4
Human 2
Sheep 1
Goat 1
Monkey 1

Breeds Most Affected

Domestic (unspecified) 61
Crossbred Canine/dog 19
Domestic Shorthair 19
Retriever - Labrador 14
Holstein-Friesian also known as Holstein 12
Cattle (other) 12
Chihuahua 12
Dog (unknown) 11
Cattle (unknown) 9
Cat (unknown) 9

Associated Drugs

Cefovecin Sodium 27
Milbemycin Oxime + Spinosad 25
Dexmedetomidine Hydrochloride 19
Spinosad 17
Pimobendan 16
Methylprednisolone Acetate 15
Moxidectin 15
Propofol 12
Melarsomine Dihydrochloride 11
Sevoflurane 9
Monensin Sodium 9
Isoflurane 8
Cefovecin 8
Meloxicam 8
Carprofen 7
Robenacoxib 7
Selamectin 6
Ketamine Hydrochloride 6
Firocoxib 6
Maropitant Citrate 6

Lung oedema Reaction Insights

367 reports name Lung oedema; 228 recorded a death outcome (62.1% of reported events, not a population-level mortality rate). VeDDRA code: 849.

By species: Dog (191 reports), Cat (110 reports), Cattle (51 reports). By breed: Domestic (unspecified) (61), Crossbred Canine/dog (19), Domestic Shorthair (19).

Most co-reported drugs: Cefovecin Sodium (27 reports), Milbemycin Oxime + Spinosad (25 reports), Dexmedetomidine Hydrochloride (19 reports), Spinosad (17 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.