Reaction profile

The FDA adverse-event record for ischaemia nos

Name: Ischaemia NOS - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

10 FDA reports name ischaemia nos, a lower-volume reaction in the CVM extract (VeDDRA 230). Plate stamps and neighbourhood peers follow.

#2459 of 2,481
by report volume (all reactions): 10
reports citing this reaction: 50.0%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ischaemia NOS has 10 reports now versus 10 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ischaemia NOS changes

FDA AER · VeDDRA plate

Code 230 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 10 reports
DEATH-HOT 50.0%
BOTTOM-DECILE #2459/2481
PHOTO-FINISH Anoxia
SPECIES-DOG Dog · 7
DRUG-LEAD Oclacitinib Malea… · 2
DESK-WIDE 10 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Anoxia (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Ischaemia NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Ischaemia NOS

Ischaemia NOS: high death-coded share in the FDA AER plate

Signature read: 10 reports place Ischaemia NOS in the lower third of FDA AER volume (#2459 of 2,481). Report volume is lower-third scale: 10 named reports in the openFDA extract. Death-coded share is upper-third: 5 of 10 reports (50.0% of named reports). Nearest volume peer: Anoxia (±0 reports). Lead species Dog (7). Lead co-reported drug Oclacitinib Maleate (2).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 7

Cat 2

Human 1

Breeds Most Affected

Shih Tzu 1

Unknown 1

Terrier - Airedale 1

Maltese 1

Terrier - Bull - American Pit 1

Schnauzer - Miniature 1

Rottweiler 1

Poodle (unspecified) 1

Domestic Shorthair 1

Domestic Mediumhair 1

Associated Drugs

Oclacitinib Maleate 2

Isoflurane 2

Spinosad 1

Ivermectin 1

Cefovecin Sodium 1

Triamcinolone Acetonide 1

Fipronil 1

Medicated Shampoo (Unknown) 1

Dexdomitor/Torbugesic Combination 1

Tilmicosin Phosphate 1

Fentanyl 1

Maropitant Citrate 1

Fluralaner Chew Tablets 1

Orbiflox/Momet/Posaco Eardrops 1

Carprofen 1

Joint Supplement 1

Fluralaner 1

Robenacoxib 1

Buprenorphine 1

Propofol 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ischaemia NOS (#2459 of 2,481 by report volume); death-coded 50.0%. PlainBreed reaction plate · report volume stamp 10 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →