Reaction profile

The FDA adverse-event record for ear canal erythema

309 FDA adverse-event reports reference ear canal erythema (VeDDRA 2566). See the species, breeds, and drugs most associated with it below.

309
reports citing this reaction
1.6%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
309
Total Reports
5
Deaths
1.6%
Death Rate

Species Most Affected

Dog 283
Cat 26

Breeds Most Affected

Retriever - Golden 35
Retriever - Labrador 28
Crossbred Canine/dog 22
Domestic Shorthair 16
Shepherd Dog - German 14
Shih Tzu 13
Poodle - Standard 10
Maltese 9
Pit Bull 9
Terrier - Yorkshire 9

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 94
Genta/Momet/Clotrim Ear Oint 30
Florfenicol + Mometasone Furoate + Terbinafine 20
Betamethasone + Florfenicol + Terbinafine 19
Afoxolaner 19
Gabapentin 18
Milbemycin Oxime + Spinosad 17
Prednisone 17
Oclacitinib Maleate 14
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 13
Carprofen 13
Orbiflox/Momet/Posaco Eardrops 12
Dexamethasone + Neomycin Sulfate + Thiabendazole 12
Diphenhydramine 10
Moxidectin 10
Maropitant Citrate 10
Ear Cleaner 9
Salicylic Acid 9
Enrofloxacin + Silver Sulfadiazine 8
Ear Cleaner (Unknown) 8

Ear canal erythema Reaction Insights

309 reports name Ear canal erythema; 5 recorded a death outcome (1.6% of reported events, not a population-level mortality rate). VeDDRA code: 2566.

By species: Dog (283 reports), Cat (26 reports). By breed: Retriever - Golden (35), Retriever - Labrador (28), Crossbred Canine/dog (22).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (94 reports), Genta/Momet/Clotrim Ear Oint (30 reports), Florfenicol + Mometasone Furoate + Terbinafine (20 reports), Betamethasone + Florfenicol + Terbinafine (19 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.