Reaction profile

The FDA adverse-event record for hypovolaemia

47 FDA reports name hypovolaemia, a lower-volume reaction in the CVM extract (VeDDRA 2614). Plate stamps and neighbourhood peers follow.

#1773 of 2,481
by report volume (all reactions)
47
reports citing this reaction
44.7%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hypovolaemia has 47 reports now versus 45 in that prior snapshot: 2 more (4.4%).

Report change
+2
Death-coded reports
+1
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hypovolaemia changes

FDA AER · VeDDRA plate

Code 2614 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 47 reports
  • DEATH-HOT 44.7%
  • MID-PACK #1773/2481
  • PHOTO-FINISH Abnormal number of of…
  • SPECIES-DOG Dog · 42
  • DRUG-LEAD Maropitant · 8
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal number of offspring (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Hypovolaemia

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal number of of… · near47ALBUMIN/GLOBULIN RATI… · near47ANISOCYTOSIS · near47Blood in trachea · near47Hypovolaemia · this reaction47Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hypovolaemia

Hypovolaemia: high death-coded share in the FDA AER plate

Signature read: Hypovolaemia's 44.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 47 named reports in the openFDA extract. Death-coded share is upper-third: 21 of 47 reports (44.7% of named reports). Nearest volume peer: Abnormal number of offspring (±0 reports). Lead species Dog (42). Lead co-reported drug Maropitant (8).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 42
Cat 5

Breeds Most Affected

Retriever - Labrador 9
Rottweiler 4
Retriever - Golden 4
Terrier - Yorkshire 3
Collie - Border 2
Shepherd Dog - German 2
Beagle 2
Domestic Shorthair 2
Cat (unknown) 2
Poodle (unspecified) 2

Associated Drugs

Maropitant 8
Meloxicam 7
Maropitant Citrate 7
Ondansetron 7
Midazolam 7
Buprenorphine 6
Propofol 6
Gabapentin 6
Hydromorphone 5
Isoflurane 4
Acetaminophen 4
Omeprazole 4
Trazodone 4
Atropine 4
Ketamine 4
Fluids 3
Prednisone 3
Enrofloxacin 3
Methadone 3
Deracoxib 3

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hypovolaemia (#1773 of 2,481 by report volume); death-coded 44.7%. PlainBreed reaction plate · death-coded share stamp 44.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →