Reaction profile

The FDA adverse-event record for hco3 low, blood

Name: HCO3 LOW, BLOOD - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

25 FDA reports name hco3 low, blood, a lower-volume reaction in the CVM extract (VeDDRA 99262). Plate stamps and neighbourhood peers follow.

#2070 of 2,481
by report volume (all reactions): 25
reports citing this reaction: 40.0%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. HCO3 LOW, BLOOD has 25 reports now versus 24 in that prior snapshot: 1 more (4.2%).

Report change: +1
Death-coded reports: +1
Death-coded share: +2.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to HCO3 LOW, BLOOD changes

FDA AER · VeDDRA plate

Code 99262 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 25 reports
DEATH-HOT 40.0%
LOWER-Q #2070/2481
PHOTO-FINISH Abnormal behaviour NOS
SPECIES-DOG Dog · 18
DRUG-LEAD Spinosad · 3
DESK-WIDE 15 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal behaviour NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around HCO3 LOW, BLOOD

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around HCO3 LOW, BLOOD

HCO3 LOW, BLOOD: high death-coded share in the FDA AER plate

Signature read: 25 reports place HCO3 LOW, BLOOD in the lower third of FDA AER volume (#2070 of 2,481). Report volume is lower-third scale: 25 named reports in the openFDA extract. Death-coded share is upper-third: 10 of 25 reports (40.0% of named reports). Nearest volume peer: Abnormal behaviour NOS (±0 reports). Lead species Dog (18). Lead co-reported drug Spinosad (3).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 18

Cat 7

Breeds Most Affected

Domestic (unspecified) 6

Crossbred Canine/dog 5

Schnauzer (unspecified) 2

Griffon - Brussels 1

Poodle (unspecified) 1

Lhasa Apso 1

Newfoundland 1

Rottweiler 1

Dachshund (unspecified) 1

Setter - Irish Red 1

Associated Drugs

Spinosad 3

Meloxicam 3

Carprofen 3

Firocoxib 2

Fomepizole 1

Ivermectin, Pyrantel 1

Deracoxib 1

Maropitant 1

Desoxycorticosterone Pivalate 1

Nitenpyram 1

Cefovecin Sodium 1

Cyclosporine A 1

Robenacoxib 1

Firocoxib 227 Mg Chewable 1

Ivermectin/Pyrantel Pamoate Chewable 136Mcg/326Mg 1

Ivermectin + Pyrantel 1

Amoxicillin Anhydrous + Clavulanic Acid 1

Potassium Phosphate 1

Methocarbamol 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for HCO3 LOW, BLOOD (#2070 of 2,481 by report volume); death-coded 40.0%. PlainBreed reaction plate · report volume stamp 25 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →