Reaction profile

The FDA adverse-event record for hip dysplasia

64 FDA adverse-event reports reference hip dysplasia (VeDDRA 2725). See the species, breeds, and drugs most associated with it below.

64
reports citing this reaction
20.3%
death-coded share
Dog
most-affected species
Afoxolaner
most-associated drug
Verify with FDA CVM →
64
Total Reports
13
Deaths
20.3%
Death Rate

Species Most Affected

Dog 61
Cat 3

Breeds Most Affected

Retriever - Labrador 9
Shepherd Dog - German 7
Dog (unknown) 6
Retriever - Golden 3
Pit Bull 3
Bulldog - French 2
Boxer (German Boxer) 2
Collie - Border 2
Spaniel - King Charles Cavalier 2
Newfoundland 2

Associated Drugs

Afoxolaner 10
Oclacitinib Maleate 8
Bedinvetmab 8
Grapiprant 7
Milbemycin Oxime + Spinosad 6
Fluralaner 13.64% 12-Week Chew 6
Moxidectin 5
Gabapentin 5
Milbemycin Oxime + Praziquantel 5
Carprofen 5
Ivermectin + Pyrantel As Pamoate Salt 4
Tramadol 3
Trilostane 3
Pyrantel Pamoate;Sarolaner 3
Polysulfated Glycosaminoglycan 2
Recombitek Lyme - 2126.R0 2
Sarolaner 2
Anti-Il31 Mab Mcs Lot #1283563 2
Canine Interleukin-31 Monoclonal Antibody 2
Sedative (Unknown) 2

Hip dysplasia Reaction Insights

64 reports name Hip dysplasia; 13 recorded a death outcome (20.3% of reported events, not a population-level mortality rate). VeDDRA code: 2725.

By species: Dog (61 reports), Cat (3 reports). By breed: Retriever - Labrador (9), Shepherd Dog - German (7), Dog (unknown) (6).

Most co-reported drugs: Afoxolaner (10 reports), Oclacitinib Maleate (8 reports), Bedinvetmab (8 reports), Grapiprant (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.