Reaction profile

The FDA adverse-event record for not defecating

169 FDA adverse-event reports reference not defecating (VeDDRA 3066). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1129 of 2,481
by report volume (all reactions)
169
reports citing this reaction
23.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Not defecating has 169 reports now versus 142 in that prior snapshot: 27 more (19.0%).

Report change
+27
Death-coded reports
+5
Death-coded share
−1.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Not defecating changes

FDA AER · VeDDRA plate

Code 3066 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 169 reports
  • DEATH-HOT 23.7%
  • MID-PACK #1129/2481
  • PHOTO-FINISH Administration device…
  • SPECIES-DOG Dog · 104
  • DRUG-LEAD Buprenorphine · 30
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Administration device NOS, damaged (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Not defecating

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Administration device… · near169Corneal oedema · near169Inappropriate packagi… · near169Loss of condition sco… · near169Not defecating · this reacti…169Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Not defecating

What the FDA AER plate says about Not defecating

Signature read: 40 death-coded reports is a heavy tail count for Not defecating in the CVM extract. Report volume sits in the middle third of the reaction corpus. 40 of 169 reports were death-coded (23.7% of named reports, not a population mortality rate). Nearest volume peer: Administration device NOS, damaged (±0 reports). Lead species Dog (104). Lead co-reported drug Buprenorphine (30).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Buprenorphine appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 104
Cat 64
Horse 1

Breeds Most Affected

Domestic Shorthair 42
Chihuahua 9
Bulldog - French 7
Retriever - Labrador 6
Retriever - Golden 5
Shih Tzu 5
Cat (unknown) 5
Terrier (unspecified) 4
Domestic Mediumhair 4
Crossbred Canine/dog 4

Associated Drugs

Buprenorphine 30
Bedinvetmab 30
Maropitant Citrate 27
Gabapentin 17
Carprofen 16
Prednisone 13
Frunevetmab 12
Diphenhydramine 11
Butorphanol 11
Dexamethasone 10
Pyrantel Pamoate;Sarolaner 10
Isoflurane 9
Fluid Therapy 9
Subcutaneous Fluids 9
Cefovecin 9
Capromorelin 9
Tigilanol Tiglate 8
Ondansetron 7
Dexmedetomidine 7
Sucralfate 7

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Not defecating, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (23.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Not defecating (#1129 of 2,481 by report volume); death-coded 23.7%. PlainBreed reaction plate · death-coded report count stamp 40 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →