Reaction profile

The FDA adverse-event record for not defecating

118 FDA adverse-event reports reference not defecating (VeDDRA 3066). See the species, breeds, and drugs most associated with it below.

118
reports citing this reaction
19.5%
death-coded share
Dog
most-affected species
Buprenorphine
most-associated drug
Verify with FDA CVM →
118
Total Reports
23
Deaths
19.5%
Death Rate

Species Most Affected

Dog 70
Cat 47
Horse 1

Breeds Most Affected

Domestic Shorthair 33
Chihuahua 6
Retriever - Golden 5
Bulldog - French 5
Cat (unknown) 5
Domestic Mediumhair 4
Crossbred Canine/dog 4
Saint Bernard Dog 4
Terrier (unspecified) 3
Schnauzer - Miniature 3

Associated Drugs

Buprenorphine 24
Bedinvetmab 20
Maropitant Citrate 18
Gabapentin 15
Carprofen 11
Frunevetmab 11
Diphenhydramine 8
Prednisone 8
Butorphanol 8
Isoflurane 8
Fluid Therapy 8
Ondansetron 6
Tigilanol Tiglate 6
Metronidazole 6
Capromorelin 6
Pyrantel Pamoate;Sarolaner 6
Famotidine 5
Dexmedetomidine 5
Atipamezole 5
Dexamethasone 5

Not defecating Reaction Insights

118 reports name Not defecating; 23 recorded a death outcome (19.5% of reported events, not a population-level mortality rate). VeDDRA code: 3066.

By species: Dog (70 reports), Cat (47 reports), Horse (1 reports). By breed: Domestic Shorthair (33), Chihuahua (6), Retriever - Golden (5).

Most co-reported drugs: Buprenorphine (24 reports), Bedinvetmab (20 reports), Maropitant Citrate (18 reports), Gabapentin (15 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.