Reaction profile

The FDA adverse-event record for ineffective, cognitive dysfunc

54 FDA adverse-event reports reference ineffective, cognitive dysfunc (VeDDRA 99092). See the species, breeds, and drugs most associated with it below.

54
reports citing this reaction
0.0%
death-coded share
Dog
most-affected species
Selegiline Hcl
most-associated drug
Verify with FDA CVM →
54
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Dog 54

Breeds Most Affected

Dog (unknown) 7
Crossbred Canine/dog 5
Retriever - Labrador 5
Beagle 3
Siberian Husky 3
Terrier - Fox (unspecified) 2
Schnauzer - Miniature 2
Shepherd Dog - Australian 2
Cattle Dog (unspecified) 2
Pekingese 2

Associated Drugs

Selegiline Hcl 41
Selegiline 15
Firocoxib 3
Deracoxib 2
Tramadol 2
Prescription Diet (Unspecified) 2
Fluoxetine Hydrochloride 2
Cyclosporine 2
Carprofen 2
Alprazolam 2
Famotidine 1
Phenylpropanolamine 1
Benazepril Hydrochloride 1
Trilostane 1
Levothyroxine Sodium 1
Anti-Inflamatory 1
Milbemycin Oxime + Spinosad 1
Diphenhydramine 1
Trazodone 1
Sam-E, Silybin, Vitamin E, Zinc 1

INEFFECTIVE, COGNITIVE DYSFUNC Reaction Insights

54 reports name INEFFECTIVE, COGNITIVE DYSFUNC; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). VeDDRA code: 99092.

By species: Dog (54 reports). By breed: Dog (unknown) (7), Crossbred Canine/dog (5), Retriever - Labrador (5).

Most co-reported drugs: Selegiline Hcl (41 reports), Selegiline (15 reports), Firocoxib (3 reports), Deracoxib (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.