Application site irritation
VeDDRA Code: 24
1,812 adverse event reports referencing this reaction
1,812
Total Reports
13
Deaths
70.0%
Death Rate
Species Most Affected
Cat 1,377
Dog 354
Human 43
Horse 29
Cattle 5
Unknown 3
Bobcat 1
Breeds Most Affected
Domestic Shorthair 892
Domestic Longhair 106
Domestic Mediumhair 73
Cat (unknown) 69
Unknown 48
Cat (other) 47
Siamese 43
Maine Coon 36
Retriever - Labrador 36
Crossbred Canine/dog 35
Associated Drugs
Selamectin 568
Selamectin;Sarolaner 305
Fluralaner Spot-On Solution 189
Imidacloprid + Moxidectin 142
Mirtazapine 77
Emodepside + Praziquantel 76
Fluralaner/Moxidectin Spot-On 73
Ivermectin + Pyrantel As Pamoate Salt 54
Fipronil 10%/S Methoprene 9% Spot On 49
Eprinomectin + Esafoxolaner + Praziquantel 38
Flumethrin-Imidacloprid 35
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 33
Buprenorphine 28
Fipronil 9.8%/S-Methoprene 8.8%/ Amitraz 22.1% Spot-On 22
Fipronil 9.8%/S-Methoprene 8.8%/Cyphenothrin 5.2% Squeeze-On 22
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 20
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 18
Rabies Vaccine 16
Chlorhexidine Gluconate + Climbazole + Phytosphingosine Salicyloyl 14
Prednisone 13
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.