Reaction profile

The FDA adverse-event record for vulvovaginitis

21 FDA reports name vulvovaginitis, a lower-volume reaction in the CVM extract (VeDDRA 824). Plate stamps and neighbourhood peers follow.

#2154 of 2,481
by report volume (all reactions)
21
reports citing this reaction
0.0%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Vulvovaginitis has 21 reports now versus 20 in that prior snapshot: 1 more (5.0%).

Report change
+1
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Vulvovaginitis changes

FDA AER · VeDDRA plate

Code 824 VOL-TRACE

VOL-TRACE · DEATH-RARE · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 21 reports
  • DEATH-RARE 0.0%
  • LOWER-Q #2154/2481
  • PHOTO-FINISH Chewing - pruritus
  • SPECIES-DOG Dog · 20
  • DRUG-LEAD Estriol Tablets · 5
  • DESK-WIDE 16 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Chewing - pruritus (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Vulvovaginitis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Chewing - pruritus · near21Deterioration of musc… · near21External teat disorder · near21Heart disorder aggrav… · near21Vulvovaginitis · this reacti…21Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Vulvovaginitis

Vulvovaginitis: low death-coded share in the FDA AER plate

Signature read: Vulvovaginitis's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is lower-third scale: 21 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 21 reports (0.0% of named reports). Nearest volume peer: Chewing - pruritus (±0 reports). Lead species Dog (20). Lead co-reported drug Estriol Tablets (5).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Estriol Tablets appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 20
Cattle 1

Breeds Most Affected

Dog (unknown) 3
Retriever - Golden 3
Bullmastiff 2
Cattle (unknown) 1
Pug 1
Corgi (unspecified) 1
Weimaraner 1
Terrier - Irish Soft-coated Wheaten 1
Spitz (unspecified) 1
Chihuahua 1

Associated Drugs

Estriol Tablets 5
Bedinvetmab 5
Afoxolaner 3
Gabapentin 3
Milbemycin, Praziquantel 2
Progesterone 1
Chlorhexidine Diacetate 1
Lufenuron + Milbemycin Oxime 1
Desoxycorticosterone Pivalate 1
Milbemycin Oxime 1
Fipronil 1
Cyclosporine 1
Glucosamine 1
Cyclosporine A 1
Glucosamine Supplement 1
Milbemycin Oxime + Spinosad 1
Rabacfosadine Succinate 1
Genta/Momet/Clotrim Ear Oint 1
Praziquantel + Pyrantel Pamoate 1
Fluralaner 13.64% 12-Week Chew 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Vulvovaginitis (#2154 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →