Reaction profile

The FDA adverse-event record for lens opacity

53 FDA reports name lens opacity, a lower-volume reaction in the CVM extract (VeDDRA 443). Plate stamps and neighbourhood peers follow.

#1709 of 2,481
by report volume (all reactions)
53
reports citing this reaction
13.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lens opacity has 53 reports now versus 52 in that prior snapshot: 1 more (1.9%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lens opacity changes

FDA AER · VeDDRA plate

Code 443 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 53 reports
  • DEATH-ELEV 13.2%
  • MID-PACK #1709/2481
  • PHOTO-FINISH Bloody foam in mouth…
  • SPECIES-DOG Dog · 49
  • DRUG-LEAD Trilostane · 25
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Bloody foam in mouth and nose (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Lens opacity

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Bloody foam in mouth… · near53Decreased skin turgor · near53Easily startled · near53Footpad disorder NOS · near53Lens opacity · this reaction53Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lens opacity

What the FDA AER plate says about Lens opacity

Signature read: 53 reports place Lens opacity in the lower third of FDA AER volume (#1709 of 2,481). Report volume is lower-third scale: 53 named reports in the openFDA extract. 7 of 53 reports were death-coded (13.2% of named reports, not a population mortality rate). Nearest volume peer: Bloody foam in mouth and nose (±0 reports). Lead species Dog (49). Lead co-reported drug Trilostane (25).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 49
Cat 3
Goat 1

Breeds Most Affected

Chihuahua 5
Retriever - Labrador 5
Crossbred Canine/dog 5
Maltese 3
Spitz - German Pomeranian 2
Schnauzer - Miniature 2
Dachshund (unspecified) 2
Beagle 2
Dog (unknown) 2
Dog (other) 1

Associated Drugs

Trilostane 25
Milbemycin Oxime + Spinosad 10
Fluralaner 5
Ivermectin 4
Milbemycin Oxime 4
Lotilaner 4
Recombinant Human Insulin 3
Carprofen 3
Afoxolaner 3
Tramadol 3
Bordetella Vaccine 3
Enrofloxacin 2
Dorzolamide Hcl & Timolol Maleate 2
Loratidine 2
Ivermectin + Pyrantel As Pamoate Salt 2
Sarolaner 2
Moxidectin 2
Rabies Vaccine 2
Leptospirosis Vaccine 2
Ursodiol 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lens opacity, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lens opacity (#1709 of 2,481 by report volume); death-coded 13.2%. PlainBreed reaction plate · report volume stamp 53 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →