Tubes, Damaged

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VeDDRA Code: 99028

1,081 adverse event reports referencing this reaction

1,081
Total Reports
1
Deaths
10.0%
Death Rate

Species Most Affected

Unknown 1,056
Human 15
Cat 5
Dog 4
Cattle 1

Breeds Most Affected

Unknown 1,071
Cat (other) 2
Domestic (unspecified) 1
Himalayan 1
Maine Coon 1
Holstein-Friesian also known as Holstein 1
Spitz - German Pomeranian 1
Schnauzer - Miniature 1
Spaniel - Cocker English 1
Terrier - West Highland White 1

Associated Drugs

Cyclosporin Ointment 385
Selamectin 244
Selamectin;Sarolaner 122
Fluralaner Spot-On Solution 46
Omeprazole 38
Cyclosporine 33
Cephapirin Benzathine 24
Imidacloprid + Moxidectin 24
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 21
Cephapirin Sodium 16
Mirtazapine 14
Milbemycin Oxime 13
Emodepside + Praziquantel 12
Milbemycin Oxime Solution 11
Genta/Betamet/Clotrim Ear Oint 11
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 8
Omeprazole 37% Oral Paste 7
Fluralaner/Moxidectin Spot-On 6
Ceftiofur Hydrochloride 5
Cloxacillin Benz Intramam Dc 4

Data Summary

Metric Value
Total reports referencing reaction 1,081
Reports with fatal outcome 1
Case-fatality rate (reported events) 10.0%
Species observed 5
Breeds observed 10
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99028.

Tubes, Damaged Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 1,081 adverse event reports that reference Tubes, Damaged as a reaction term, including 1 reports with a death outcome — a 10.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99028, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Tubes, Damaged appears most frequently in reports for Unknown (1,056 reports), Human (15 reports), Cat (5 reports) — with Unknown dominating at 1,056 entries. Within those species, the breeds most often named alongside this reaction are Unknown (1,071), Cat (other) (2), Domestic (unspecified) (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Tubes, Damaged are Cyclosporin Ointment (385 reports), Selamectin (244 reports), Selamectin;Sarolaner (122 reports), Fluralaner Spot-On Solution (46 reports), with Cyclosporin Ointment appearing alongside this reaction in 385 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial