Reaction profile

The FDA adverse-event record for tubes, damaged

1,136 FDA reports name tubes, damaged, a high-volume reaction in the CVM extract (VeDDRA 99028). Plate stamps and neighbourhood peers follow.

#354 of 2,481
by report volume (all reactions)
1,136
reports citing this reaction
0.1%
death-coded share
Unknown
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Tubes, Damaged has 1,136 reports now versus 1,123 in that prior snapshot: 13 more (1.2%).

Report change
+13
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Tubes, Damaged changes

FDA AER · VeDDRA plate

Code 99028 VOL-MID

VOL-MID · DEATH-RARE · UPPER-Q · PHOTO-FINISH · SPECIES-UNKNOWN · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,136 reports
  • DEATH-RARE 0.1%
  • UPPER-Q #354/2481
  • PHOTO-FINISH Regurgitation
  • SPECIES-UNKNOWN Unknown · 1,107
  • DRUG-LEAD Cyclosporin Ointm… · 409
  • DESK-WIDE 10 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Regurgitation (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Tubes, Damaged

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Hypothyroidism · near1137Regurgitation · near1136Tubes, Damaged · this reacti…1136Low sodium-potassium… · near1134Anaphylactic-type rea… · near1132Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Tubes, Damaged

Tubes, Damaged: low death-coded share in the FDA AER plate

Signature read: Tubes, Damaged's 0.1% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 1,136 named reports in the openFDA extract. Death-coded share is lower-third: 1 of 1,136 reports (0.1% of named reports). Nearest volume peer: Regurgitation (±0 reports). Lead species Unknown (1,107). Lead co-reported drug Cyclosporin Ointment (409).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Cyclosporin Ointment appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Unknown 1,107
Human 19
Cat 5
Dog 4
Cattle 1

Breeds Most Affected

Unknown 1,126
Cat (other) 2
Domestic (unspecified) 1
Himalayan 1
Maine Coon 1
Holstein-Friesian also known as Holstein 1
Spitz - German Pomeranian 1
Schnauzer - Miniature 1
Spaniel - Cocker English 1
Terrier - West Highland White 1

Associated Drugs

Cyclosporin Ointment 409
Selamectin 244
Selamectin;Sarolaner 133
Fluralaner Spot-On Solution 48
Omeprazole 42
Cyclosporine 33
Cephapirin Benzathine 24
Imidacloprid + Moxidectin 24
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 21
Mirtazapine 17
Cephapirin Sodium 16
Emodepside + Praziquantel 13
Milbemycin Oxime 13
Fluralaner/Moxidectin Spot-On 13
Milbemycin Oxime Solution 11
Genta/Betamet/Clotrim Ear Oint 11
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 8
Omeprazole 37% Oral Paste 7
Ceftiofur Hydrochloride 5
Buprenorphine 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Tubes, Damaged, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (0.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Tubes, Damaged (#354 of 2,481 by report volume); death-coded 0.1%. PlainBreed reaction plate · death-coded share stamp 0.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →