Reaction profile

The FDA adverse-event record for tubes, damaged

1,081 FDA adverse-event reports reference tubes, damaged (VeDDRA 99028). See the species, breeds, and drugs most associated with it below.

1,081
reports citing this reaction
0.1%
death-coded share
Unknown
most-affected species
Cyclosporin Ointment
most-associated drug
Verify with FDA CVM →
1,081
Total Reports
1
Deaths
0.1%
Death Rate

Species Most Affected

Unknown 1,056
Human 15
Cat 5
Dog 4
Cattle 1

Breeds Most Affected

Unknown 1,071
Cat (other) 2
Domestic (unspecified) 1
Himalayan 1
Maine Coon 1
Holstein-Friesian also known as Holstein 1
Spitz - German Pomeranian 1
Schnauzer - Miniature 1
Spaniel - Cocker English 1
Terrier - West Highland White 1

Associated Drugs

Cyclosporin Ointment 385
Selamectin 244
Selamectin;Sarolaner 122
Fluralaner Spot-On Solution 46
Omeprazole 38
Cyclosporine 33
Cephapirin Benzathine 24
Imidacloprid + Moxidectin 24
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 21
Cephapirin Sodium 16
Mirtazapine 14
Milbemycin Oxime 13
Emodepside + Praziquantel 12
Milbemycin Oxime Solution 11
Genta/Betamet/Clotrim Ear Oint 11
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 8
Omeprazole 37% Oral Paste 7
Fluralaner/Moxidectin Spot-On 6
Ceftiofur Hydrochloride 5
Cloxacillin Benz Intramam Dc 4

Tubes, Damaged Reaction Insights

1,081 reports name Tubes, Damaged; 1 recorded a death outcome (0.1% of reported events, not a population-level mortality rate). VeDDRA code: 99028.

By species: Unknown (1,056 reports), Human (15 reports), Cat (5 reports). By breed: Unknown (1,071), Cat (other) (2), Domestic (unspecified) (1).

Most co-reported drugs: Cyclosporin Ointment (385 reports), Selamectin (244 reports), Selamectin;Sarolaner (122 reports), Fluralaner Spot-On Solution (46 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.