Injection site necrosis
VeDDRA Code: 89
678 adverse event reports referencing this reaction
678
Total Reports
70
Deaths
1030.0%
Death Rate
Species Most Affected
Dog 535
Cat 71
Horse 35
Cattle 22
Pig 7
Other Reptiles 2
Human 2
Guinea Pig 1
Chicken 1
Other Rodents 1
Breeds Most Affected
Retriever - Labrador 53
Dog (unknown) 38
Pit Bull 35
Domestic Shorthair 35
Boxer (German Boxer) 32
Chihuahua 28
Crossbred Canine/dog 23
Retriever - Golden 21
Bulldog - French 18
Domestic (unspecified) 15
Associated Drugs
Tigilanol Tiglate 231
Carprofen 133
Enrofloxacin 61
Maropitant Citrate 48
Butorphanol 46
Gabapentin 44
Famotidine 40
Diphenhydramine 40
Cefovecin 39
Dexmedetomidine 38
Buprenorphine 36
Prednisone 36
Meloxicam 29
Ceftiofur Crystalline Free Acid 28
Atipamezole 27
Melarsomine Dihydrochloride 22
Isoflurane 22
Dexmedetomidine Hydrochloride 20
Propofol 20
Moxidectin 18
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.