Reaction profile

The FDA adverse-event record for suspension, abnormal

3,379 FDA adverse-event reports reference suspension, abnormal (VeDDRA 99024). See the species, breeds, and drugs most associated with it below.

3,379
reports citing this reaction
0.3%
death-coded share
Unknown
most-affected species
Amoxicillin, Clavulanate
most-associated drug
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3,379
Total Reports
11
Deaths
0.3%
Death Rate

Species Most Affected

Unknown 3,243
Dog 77
Cat 46
Cattle 10
Horse 3

Breeds Most Affected

Unknown 3,244
Domestic Shorthair 24
Crossbred Canine/dog 19
Dog (unknown) 11
Domestic (unspecified) 8
Holstein-Friesian also known as Holstein 6
Terrier - Jack Russell 5
Retriever - Labrador 5
Cat (unknown) 4
Schnauzer - Miniature 3

Associated Drugs

Amoxicillin, Clavulanate 584
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 535
Moxidectin 440
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 246
Insulin Injectable Vial 207
Ceftiofur Sodium 141
Triamcinolone Acetonide 121
Amoxicillin As Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 120
Amoxicillin As Trihydrate; Clavulanate Potassium ( K-Clavulanate) 85
Ceftiofur Hydrochloride 75
Penicillin G Procaine 71
Recombinant Human Insulin 70
Cefovecin 61
Methylprednisolone Acetate 57
Porcine Insulin 54
Propofol 48
Human Insulin 42
Meloxicam 28
Protamine Zinc Recombinant Human Insulin 26
Amoxicillin (As Trihydrate); Clavulanate Potassium ( K-Clavulanate) 24

Suspension, Abnormal Reaction Insights

3,379 reports name Suspension, Abnormal; 11 recorded a death outcome (0.3% of reported events, not a population-level mortality rate). VeDDRA code: 99024.

By species: Unknown (3,243 reports), Dog (77 reports), Cat (46 reports). By breed: Unknown (3,244), Domestic Shorthair (24), Crossbred Canine/dog (19).

Most co-reported drugs: Amoxicillin, Clavulanate (584 reports), Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) (535 reports), Moxidectin (440 reports), Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) (246 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.