Reaction profile

The FDA adverse-event record for corneal oedema

169 FDA adverse-event reports reference corneal oedema (VeDDRA 413). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1126 of 2,481
by report volume (all reactions)
169
reports citing this reaction
10.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Corneal oedema has 169 reports now versus 168 in that prior snapshot: 1 more (0.6%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Corneal oedema changes

FDA AER · VeDDRA plate

Code 413 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 169 reports
  • DEATH-ELEV 10.1%
  • MID-PACK #1126/2481
  • PHOTO-FINISH Administration device…
  • SPECIES-DOG Dog · 136
  • DRUG-LEAD Maropitant Citrate · 20
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Administration device NOS, damaged (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Corneal oedema

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Administration device… · near169Corneal oedema · this reacti…169Inappropriate packagi… · near169Loss of condition sco… · near169Not defecating · near169Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Corneal oedema

What the FDA AER plate says about Corneal oedema

Signature read: death-coded share at 10.1% is the most distinctive outcome stamp on Corneal oedema. Report volume sits in the middle third of the reaction corpus. 17 of 169 reports were death-coded (10.1% of named reports, not a population mortality rate). Nearest volume peer: Administration device NOS, damaged (±0 reports). Lead species Dog (136). Lead co-reported drug Maropitant Citrate (20).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Maropitant Citrate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 136
Cat 19
Cattle 8
Human 3
Horse 3

Breeds Most Affected

Shih Tzu 20
Crossbred Canine/dog 9
Retriever - Labrador 9
Domestic Shorthair 8
Terrier - Yorkshire 7
Spaniel - Cocker American 5
Terrier - Boston 5
Schnauzer - Miniature 5
Chihuahua 4
Cat (unknown) 4

Associated Drugs

Maropitant Citrate 20
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 18
Oclacitinib Maleate 15
Prednisone 12
Carprofen 11
Isoflurane 10
Enrofloxacin 10
Afoxolaner 9
Fluids 9
Cyclosporine 8
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 8
Fluralaner Chew Tablets 8
Eye Lubricant 8
Moxidectin 7
Diphenhydramine 7
Ofloxacin 7
Spinosad 6
Tramadol 6
Gabapentin 6
Buprenorphine 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Corneal oedema, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (10.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Corneal oedema (#1126 of 2,481 by report volume); death-coded 10.1%. PlainBreed reaction plate · death-coded share stamp 10.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →